Abstract Withania somnifera (L.) Dunal (Solanaceae) has been used as a traditional
Rasayana herb for a long time. Traditional uses of this plant indicate its ameliorative …

Many developed countries are experiencing a rapidly “greying” population, and cognitive
decline is common in the elderly. There is no cure for dementia, and pharmacotherapy …

Currently, definitive treatment for neurodegenerative diseases without side effects has not
been developed, therefore, exploring natural polysaccharides with neuroprotection to …

The rotenone-induced animal model of Parkinson's disease (PD) has been used to
investigate the pathogenesis of PD. Oxidative stress is one of the main contributors of …

Neurodegenerative disorders like Alzheimer's disease, Huntington's disease, Parkinson's
disease, spinocerebellar ataxias, amyotrophic lateral sclerosis, frontotemporal dementia to …

Background: Age-related cognitive decline has been suggested to result from an increase in
the brain neuron loss, which is attributable to continued derangement of the brain's …

Abstract Background Withania somnifera (L.) Dunal (W. somnifera) is a herb commonly
known by its English name as Winter Cherry. Africa is indigenous to many medicinal plants …

Background Systemic inflammation driven neuroinflammation is an event which correlates
with pathogenesis of several neurodegenerative diseases. Therefore, targeting peripheral …

Reactive gliosis, microgliosis, and subsequent secretion of various inflammatory mediators
like cytokines, proteases, reactive oxygen, and nitrogen species are the suggested key …

Background The epidemic of obesity has reached alarming levels in both develo** and
developed nations. Excessive calorie intake and sedentary lifestyle due to technological …