Fibromyalgia: pathogenesis, mechanisms, diagnosis and treatment options update

R Siracusa, RD Paola, S Cuzzocrea… - International journal of …, 2021 - mdpi.com
Fibromyalgia is a syndrome characterized by chronic and widespread musculoskeletal pain,
often accompanied by other symptoms, such as fatigue, intestinal disorders and alterations …

Fibromyalgia: an update on clinical characteristics, aetiopathogenesis and treatment

P Sarzi-Puttini, V Giorgi, D Marotto… - Nature Reviews …, 2020 - nature.com
Fibromyalgia is characterized by chronic widespread pain, fatigue, sleep disturbances and
functional symptoms. The etiopathogenesis, diagnostic criteria and classification criteria of …

Deciphering nociplastic pain: clinical features, risk factors and potential mechanisms

CM Kaplan, E Kelleher, A Irani, A Schrepf… - Nature Reviews …, 2024 - nature.com
Nociplastic pain is a mechanistic term used to describe pain that arises or is sustained by
altered nociception, despite the absence of tissue damage. Although nociplastic pain has …

[HTML][HTML] AAPT diagnostic criteria for fibromyalgia

LM Arnold, RM Bennett, LJ Crofford, LE Dean… - The journal of pain, 2019 - Elsevier
Fibromyalgia (FM) is a common chronic pain disorder that presents diagnostic challenges
for clinicians. Several classification, diagnostic and screening criteria have been developed …

Low back pain in older adults: risk factors, management options and future directions

AYL Wong, J Karppinen, D Samartzis - Scoliosis and spinal disorders, 2017 - Springer
Low back pain (LBP) is one of the major disabling health conditions among older adults
aged 60 years or older. While most causes of LBP among older adults are non-specific and …

[HTML][HTML] Assessment of chronic pain: domains, methods, and mechanisms

RB Fillingim, JD Loeser, R Baron, RR Edwards - The journal of pain, 2016 - Elsevier
Accurate classification of chronic pain conditions requires reliable and valid pain
assessment. Moreover, pain assessment serves several additional functions, including …

[HTML][HTML] The association of sleep and pain: an update and a path forward

PH Finan, BR Goodin, MT Smith - The journal of pain, 2013 - Elsevier
Ample evidence suggests that sleep and pain are related. However, many questions remain
about the direction of causality in their association, as well as mechanisms that may account …

Cognitive and emotional control of pain and its disruption in chronic pain

MC Bushnell, M Čeko, LA Low - Nature reviews neuroscience, 2013 - nature.com
Chronic pain is one of the most prevalent health problems in our modern world, with millions
of people debilitated by conditions such as back pain, headache and arthritis. To address …

Descending pain modulation and chronification of pain

MH Ossipov, K Morimura, F Porreca - Current opinion in …, 2014 - journals.lww.com
Preclinical studies coupled with clinical pharmacologic and neuroimaging investigations
have advanced our understanding of brain circuits that modulate pain. Descending pain …

When pain gets stuck: the evolution of pain chronification and treatment resistance

D Borsook, AM Youssef, L Simons, I Elman… - Pain, 2018 - journals.lww.com
It is well-recognized that, despite similar pain characteristics, some people with chronic pain
recover, whereas others do not. In this review, we discuss possible contributions and …