Hypervirulent and carbapenem-resistant Klebsiella pneumoniae: A global public health threat
T Lei, B Liao, LR Yang, Y Wang, X Chen - Microbiological Research, 2024 - Elsevier
The evolution of hypervirulent and carbapenem-resistant Klebsiella pneumoniae can be
categorized into three main patterns: the evolution of KL1/KL2-hvKp strains into CR-hvKp …
categorized into three main patterns: the evolution of KL1/KL2-hvKp strains into CR-hvKp …
Antibiotic resistance: A global problem and the need to do more
FC Lessa, DM Sievert - Clinical Infectious Diseases, 2023 - academic.oup.com
The discovery of penicillin in 1928 and its initial use in the 1940s to treat serious infections
marked a turning point in modern medicine saving millions of lives [1]. However, antibiotic …
marked a turning point in modern medicine saving millions of lives [1]. However, antibiotic …
An increased prevalence of carbapenem-resistant hypervirulent Klebsiella pneumoniae associated with the COVID-19 pandemic
C Liu, J Guo, S Fan, W Guo, H Qi, S Baker, P Du… - Drug Resistance …, 2024 - Elsevier
Abstract Background Klebsiella pneumoniae (Kp) is a common community-acquired and
nosocomial pathogen. Carbapenem-resistant and hypervirulent (CR-hvKp) variants can …
nosocomial pathogen. Carbapenem-resistant and hypervirulent (CR-hvKp) variants can …
Costs-effectiveness and cost components of pharmaceutical and non-pharmaceutical interventions affecting antibiotic resistance outcomes in hospital patients: a …
Introduction Limited information on costs and the cost-effectiveness of hospital interventions
to reduce antibiotic resistance (ABR) hinder efficient resource allocation. Methods We …
to reduce antibiotic resistance (ABR) hinder efficient resource allocation. Methods We …
Lives lost and disease burden related to antimicrobial resistance in the Americas can no longer be ignored
The emergence and spread of antimicrobial resistance (AMR) poses a substantial risk to
modern medicine and is widely recognised as one of the most daunting challenges of our …
modern medicine and is widely recognised as one of the most daunting challenges of our …
[HTML][HTML] Impact of the COVID-19 pandemic on inpatient antibiotic and antifungal drug prescribing volumes in Germany
WV Kern, M Steib-Bauert, J Baumann, E Kramme… - Antibiotics, 2024 - mdpi.com
Background: Previous studies found that the coronavirus disease 2019 (COVID-19)
pandemic had a variable impact on the consumption of antimicrobial drugs in human …
pandemic had a variable impact on the consumption of antimicrobial drugs in human …
Prevalence of carbapenem-resistant Enterobacterales with blaIMP-6 predominance in hospitals from 2018 to 2021 in Nara, Japan
R Kishi, R Nakano, A Nakano… - JAC-Antimicrobial …, 2024 - academic.oup.com
Objectives Despite the global health risk of carbapenem-resistant Enterobacterales (CRE),
especially carbapenemase-producing Enterobacterales (CPE), Japan reports a significantly …
especially carbapenemase-producing Enterobacterales (CPE), Japan reports a significantly …
Multispecies emergence of dual blaKPC/NDM carbapenemase-producing Enterobacterales recovered from invasive infections in Chile
AM Quesille-Villalobos, C Solar… - Antimicrobial Agents …, 2025 - journals.asm.org
Carbapenemase-producing carbapenem-resistant Enterobacterales (CP-CRE) represent a
significant global threat. The emergence of dual CP-CRE is particularly alarming, as they …
significant global threat. The emergence of dual CP-CRE is particularly alarming, as they …
[HTML][HTML] Excess burden of antibiotic-resistant bloodstream infections: evidence from a multicentre retrospective cohort study in Chile, 2018–2022
Background Antibiotic-resistant bloodstream infections (ARB BSI) cause an enormous
disease and economic burden. We assessed the impact of ARB BSI caused by high-and …
disease and economic burden. We assessed the impact of ARB BSI caused by high-and …
Ceftazidime/avibactam resistance is associated with PER-3-producing ST309 lineage in Chilean clinical isolates of non-carbapenemase producing Pseudomonas …
Introduction Ceftazidime/avibactam (CZA) is indicated against multidrug-resistant
Pseudomonas aeruginosa, particularly those that are carbapenem resistant. CZA resistance …
Pseudomonas aeruginosa, particularly those that are carbapenem resistant. CZA resistance …