Polymeric materials have been extensively explored in the field of nanomedicine; within
them, poly lactic-co-glycolic acid (PLGA) holds a prominent position in micro-and …

The present article describes the state of the art in the rapidly develo** field of bone tissue
engineering, where many disciplines, such as material science, mechanical engineering …

In the determination of the bioavailability of drugs administered orally, the drugs' solubility
and permeability play a crucial role. For absorption of drug molecules and production of a …

Treating large bone defects, known as critical-sized defects (CSDs), is challenging because
they are not spontaneously healed by the patient's body. Due to the limitations associated …

Fibroblasts are cells present throughout the human body that are primarily responsible for
the production and maintenance of the extracellular matrix (ECM) within the tissues. They …

Conventional wound-dressing materials with structural and functional deficiencies are not
effective in promoting wound healing. The development of multifunctional wound dressings …

Poly (lactic-co-glycolic) acid (PLGA) has attracted considerable interest as a base material
for biomedical applications due to its:(i) biocompatibility;(ii) tailored biodegradation rate …

Tissue engineering applications commonly encompass the use of three-dimensional (3D)
scaffolds to provide a suitable microenvironment for the incorporation of cells or growth …

Bone defects requiring grafts to promote healing are frequently occurring and costly
problems in health care. Chitosan, a biodegradable, naturally occurring polymer, has drawn …

Scaffolds play a crucial role in tissue engineering. Biodegradable polymers with great
processing flexibility are the predominant scaffolding materials. Synthetic biodegradable …