[HTML][HTML] Japanese encephalitis—the prospects for new treatments

L Turtle, T Solomon - Nature Reviews Neurology, 2018 - nature.com
Japanese encephalitis is a mosquito-borne disease that occurs in Asia and is caused by
Japanese encephalitis virus (JEV), a member of the genus Flavivirus. Although many …

Pathobiology of Japanese encephalitis virus infection

KB Sharma, S Vrati, M Kalia - Molecular aspects of medicine, 2021 - Elsevier
Japanese encephalitis virus (JEV) is a flavivirus, spread by the bite of carrier Culex
mosquitoes. The subsequent disease caused is Japanese encephalitis (JE), which is the …

Lignans and Neolignans: Plant secondary metabolites as a reservoir of biologically active substances

F Zálešák, DJYD Bon, J Pospíšil - Pharmacological Research, 2019 - Elsevier
Lignans and neolignans are plant secondary metabolites derived from the oxidative
coupling of phenylpropanoids. Biological activity of these phenolic compounds ranges from …

Overview of the anti-inflammatory effects, pharmacokinetic properties and clinical efficacies of arctigenin and arctiin from Arctium lappa L

Q Gao, M Yang, Z Zuo - Acta Pharmacologica Sinica, 2018 - nature.com
Arctigenin (AR) and its glycoside, arctiin, are two major active ingredients of Arctium lappa L
(A lappa), a popular medicinal herb and health supplement frequently used in Asia. In the …

Pathogenicity and virulence of Japanese encephalitis virus: Neuroinflammation and neuronal cell damage

U Ashraf, Z Ding, S Deng, J Ye, S Cao, Z Chen - Virulence, 2021 - Taylor & Francis
Thousands of human deaths occur annually due to Japanese encephalitis (JE), caused by
Japanese encephalitis virus. During the virus infection of the central nervous system …

Flaviviridae Viruses and Oxidative Stress: Implications for Viral Pathogenesis

Z Zhang, L Rong, YP Li - Oxidative medicine and cellular …, 2019 - Wiley Online Library
Oxidative stress is induced once the balance of generation and neutralization of reactive
oxygen species (ROS) is broken in the cell, and it plays crucial roles in a variety of natural …

Japanese encephalitis virus: an update on the potential antivirals and vaccines

KS Srivastava, V Jeswani, N Pal, B Bohra… - Vaccines, 2023 - mdpi.com
Japanese encephalitis virus (JEV) is the causal agent behind Japanese encephalitis (JE), a
potentially severe brain infection that spreads through mosquito bites. JE is predominant …

Japanese encephalitis—a pathological and clinical perspective

D Ghosh, A Basu - PLoS neglected tropical diseases, 2009 - journals.plos.org
Japanese encephalitis (JE) is the leading form of viral encephalitis in Asia. It is caused by
the JE virus (JEV), which belongs to the family Flaviviridae. JEV is endemic to many parts of …

[HTML][HTML] Lignans as pharmacological agents in disorders related to oxidative stress and inflammation: chemical synthesis approaches and biological activities

DI Osmakov, AP Kalinovskii, OA Belozerova… - International journal of …, 2022 - mdpi.com
Plant lignans exhibit a wide range of biological activities, which makes them the research
objects of potential use as therapeutic agents. They provide diverse naturally-occurring …

Antibacterial synergy between rosmarinic acid and antibiotics against methicillin-resistant Staphylococcus aureus

SP Ekambaram, SS Perumal… - Journal of …, 2016 - pmc.ncbi.nlm.nih.gov
Aim/Background: Medicinal plants have ability to resist microorganisms by synthesizing
secondary metabolites such as phenols. Rosmarinic acid (RA) is a phenylpropanoid widely …