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YB‐1 protein: functions and regulation
The Y‐box binding protein 1 (YB‐1, YBX1) is a member of the family of DNA‐and RNA‐
binding proteins with an evolutionarily ancient and conserved cold shock domain. It falls into …
binding proteins with an evolutionarily ancient and conserved cold shock domain. It falls into …
Y-box-binding protein 1 (YB-1) and its functions
This review describes the structure and functions of Y-box binding protein 1 (YB-1) and its
homologs. Interactions of YB-1 with DNA, mRNAs, and proteins are considered. Data on the …
homologs. Interactions of YB-1 with DNA, mRNAs, and proteins are considered. Data on the …
VEGF-A splicing: the key to anti-angiogenic therapeutics?
SJ Harper, DO Bates - Nature Reviews Cancer, 2008 - nature.com
The physiology of microvessels limits the growth and development of tumours. Tumours gain
nutrients and excrete waste through growth-associated microvessels. New anticancer …
nutrients and excrete waste through growth-associated microvessels. New anticancer …
ZO-1 interacts with YB-1 in endothelial cells to regulate stress granule formation during angiogenesis
Abstract Zonula occludens-1 (ZO-1) is involved in the regulation of cell-cell junctions
between endothelial cells (ECs). Here we identify the ZO-1 protein interactome and uncover …
between endothelial cells (ECs). Here we identify the ZO-1 protein interactome and uncover …
Polypyrimidine-tract-binding protein: a multifunctional RNA-binding protein
K Sawicka, M Bushell, KA Spriggs… - Biochemical Society …, 2008 - portlandpress.com
PTB (polypyrimidine-tract-binding protein) is a ubiquitous RNA-binding protein. It was
originally identified as a protein with a role in splicing but it is now known to function in a …
originally identified as a protein with a role in splicing but it is now known to function in a …
VEGF-A mRNA processing, stability and translation: a paradigm for intricate regulation of gene expression at the post-transcriptional level
T Arcondéguy, E Lacazette, S Millevoi… - Nucleic acids …, 2013 - academic.oup.com
Abstract Vascular Endothelial Growth Factor A (VEGF-A) is a potent secreted mitogen crucial
for physiological and pathological angiogenesis. Post-transcriptional regulation of VEGF-A …
for physiological and pathological angiogenesis. Post-transcriptional regulation of VEGF-A …
[HTML][HTML] Y-box binding proteins in mRNP assembly, translation, and stability control
Y-box binding proteins (YB proteins) are DNA/RNA-binding proteins belonging to a large
family of proteins with the cold shock domain. Functionally, these proteins are known to be …
family of proteins with the cold shock domain. Functionally, these proteins are known to be …
Akt-mediated YB-1 phosphorylation activates translation of silent mRNA species
V Evdokimova, P Ruzanov, MS Anglesio… - … and cellular biology, 2006 - Taylor & Francis
YB-1 is a broad-specificity RNA-binding protein that is involved in regulation of mRNA
transcription, splicing, translation, and stability. In both germinal and somatic cells, YB-1 and …
transcription, splicing, translation, and stability. In both germinal and somatic cells, YB-1 and …
YBX1 promotes type H vessel–dependent bone formation in an m5C-dependent manner
YJ Li, Q Guo, MS Ye, GP Cai, WF **ao, S Deng… - JCI …, 2024 - pmc.ncbi.nlm.nih.gov
RNA-binding proteins (RBPs) interact with RNA and ubiquitously regulate RNA transcripts
during their life cycle, playing a fundamental role in the progression of angiogenesis-related …
during their life cycle, playing a fundamental role in the progression of angiogenesis-related …
[HTML][HTML] New insights into functional roles of the polypyrimidine tract-binding protein
Polypyrimidine Tract Binding Protein (PTB) is an intensely studied RNA binding protein
involved in several post-transcriptional regulatory events of gene expression. Initially …
involved in several post-transcriptional regulatory events of gene expression. Initially …