Monitoring of cerebral blood flow autoregulation: physiologic basis, measurement, and clinical implications

EL Vu, CH Brown IV, KM Brady, CW Hogue - British journal of anaesthesia, 2024‏ - Elsevier
Cerebral blood flow (CBF) autoregulation is the physiologic process whereby blood supply
to the brain is kept constant over a range of cerebral perfusion pressures ensuring a …

Continuous time-domain cerebrovascular reactivity metrics and discriminate capacity for the upper and lower limits of autoregulation: a sco** review of the animal …

AS Sainbhi, L Froese, A Gomez, C Batson… - Neurotrauma …, 2021‏ - liebertpub.com
Over a wide range of systemic arterial pressures, cerebral blood flow (CBF) is regulated
fairly constantly by the cerebral vessels in a process termed cerebral autoregulation (CA) …

Cerebral blood flow dynamics during cardiac surgery in infants

M Leth-Olsen, G Døhlen, H Torp, SA Nyrnes - Pediatric Research, 2024‏ - nature.com
Background In this pilot study, we investigated continuous cerebral blood flow velocity
measurements to explore cerebrovascular hemodynamics in infants with congenital heart …

Effect of intraoperative arterial hypotension on the risk of perioperative stroke after noncardiac surgery: A retrospective multicenter cohort study

K Wongtangman, LJ Wachtendorf, M Blank… - Anesthesia & …, 2021‏ - journals.lww.com
BACKGROUND: Intraoperative cerebral blood flow is mainly determined by cerebral
perfusion pressure and cerebral autoregulation of vasomotor tone. About 1% of patients …

Critical thresholds of long-pressure reactivity index and impact of intracranial pressure monitoring methods in traumatic brain injury

E Hong, L Froese, E Pontén, A Fletcher-Sandersjöö… - Critical Care, 2024‏ - Springer
Background Moderate-to-severe traumatic brain injury (TBI) has a global mortality rate of
about 30%, resulting in acquired life-long disabilities in many survivors. To potentially …

Comparison of different metrics of cerebral autoregulation in association with major morbidity and mortality after cardiac surgery

X Liu, J Donnelly, KM Brady, K Akiyoshi, B Bush… - British journal of …, 2022‏ - Elsevier
Background Cardiac surgery studies have established the clinical relevance of personalised
arterial blood pressure management based on cerebral autoregulation. However …

Morbidity and mortality in patients managed with high compared with low blood pressure targets during on-pump cardiac surgery: a systematic review and meta …

CC McEwen, T Amir, Y Qiu, J Young… - Canadian Journal of …, 2022‏ - Springer
Purpose Many believe that blood pressure management during cardiac surgery is
associated with postoperative outcomes. We conducted a systematic review and meta …

Optimal bispectral index level of sedation and cerebral oximetry in traumatic brain injury: a non-invasive individualized approach in critical care?

L Froese, A Gomez, AS Sainbhi, C Batson… - Intensive Care Medicine …, 2022‏ - Springer
Background Impaired cerebral autoregulation has been linked with worse outcomes, with
literature suggesting that current therapy guidelines fail to significantly impact …

Continuous monitoring of cerebral autoregulation in adults supported by extracorporeal membrane oxygenation

LQ Zhang, H Chang, A Kalra, M Humayun… - Neurocritical care, 2024‏ - Springer
Background Impaired cerebral autoregulation (CA) is one of several proposed mechanisms
of acute brain injury in patients supported by extracorporeal membrane oxygenation …

Cerebral autoregulation in pediatric and neonatal intensive care: A sco** review

M Fedriga, S Martini, FG Iodice… - Journal of Cerebral …, 2024‏ - journals.sagepub.com
Deranged cerebral autoregulation (CA) is associated with worse outcome in adult brain
injury. Strategies for monitoring CA and maintaining the brain at its 'best CA status' have …