Coronavirus disease (COVID-19): comprehensive review of clinical presentation

OP Mehta, P Bhandari, A Raut, SEO Kacimi… - Frontiers in Public …, 2021 - frontiersin.org
COVID-19 is a rapidly growing pandemic with its first case identified during December 2019
in Wuhan, Hubei Province, China. Due to the rampant rise in the number of cases in China …

[HTML][HTML] Endothelial dysfunction in COVID-19: a unifying mechanism and a potential therapeutic target

P Ambrosino, IL Calcaterra, M Mosella, R Formisano… - Biomedicines, 2022 - mdpi.com
The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) generated a
worldwide emergency, until the declaration of the pandemic in March 2020. SARS-CoV-2 …

COVID-19 pandemic and hypertension: an updated report from the Japanese Society of Hypertension project team on COVID-19

S Shibata, K Kobayashi, M Tanaka, K Asayama… - Hypertension …, 2023 - nature.com
The number of reported cases with coronavirus disease 2019 (COVID-19) has exceeded
620 million worldwide, still having a profound impact on people's health and daily lives since …

Efficacy of losartan in hospitalized patients with COVID-19–induced lung injury: a randomized clinical trial

MA Puskarich, NE Ingraham, LH Merck… - JAMA network …, 2022 - jamanetwork.com
Importance SARS-CoV-2 viral entry may disrupt angiotensin II (AII) homeostasis,
contributing to COVID-19 induced lung injury. AII type 1 receptor blockade mitigates lung …

Clinical assessment of endothelial function in convalescent COVID-19 patients: a meta-analysis with meta-regressions

P Ambrosino, S Sanduzzi Zamparelli, M Mosella… - Annals of …, 2022 - Taylor & Francis
Background Endothelial dysfunction has been proposed to play a key role in the
pathogenesis of coronavirus disease 2019 (COVID-19) and its post-acute sequelae. Flow …

Renin‐angiotensin aldosterone system inhibitors and COVID‐19: a systematic review and meta‐analysis revealing critical bias across a body of observational …

J Loader, FC Taylor, E Lampa… - Journal of the American …, 2022 - ahajournals.org
Background Renin‐angiotensin aldosterone system (RAAS) inhibitor—COVID‐19 studies,
observational in design, appear to use biased methods that can distort the interaction …

Clinical characteristics associated with mortality of COVID-19 patients admitted to an intensive care unit of a tertiary hospital in South Africa

PS Nyasulu, BT Ayele, CF Koegelenberg, E Irusen… - PloS one, 2022 - journals.plos.org
Background Over 130 million people have been diagnosed with Coronavirus disease 2019
(COVID-19), and more than one million fatalities have been reported worldwide. South …

Adverse cardiovascular effects of anti-COVID-19 drugs

D Liu, X Zeng, Z Ding, F Lv, JL Mehta… - Frontiers in …, 2021 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or COVID-19 infection is
the cause of the ongoing global pandemic. Mortality from COVID-19 infection is particularly …

Evaluation of pathophysiological relationships between renin-angiotensin and ACE-ACE2 systems in cardiovascular disorders: from theory to routine clinical practice …

A Aimo, G Vergaro, C Passino… - Critical Reviews in Clinical …, 2021 - Taylor & Francis
Despite the progressive improvements in diagnosis and therapy during the first 20 years of
this century, the morbidity and mortality of patients with heart failure (HF) remain high …

[HTML][HTML] Overreactive macrophages in SARS-CoV-2 infection: the effects of ACEI

D Felkle, K Zięba, K Kaleta, J Czaja, A Zyzdorf… - International …, 2023 - Elsevier
Among various factors influencing the course of SARS-CoV-2 infection in humans,
macrophage overactivation is considered the main cause of the cytokine storm that leads to …