Blast-related traumatic brain injury: current concepts and research considerations

DW Bryden, JI Tilghman… - Journal of experimental …, 2019 - journals.sagepub.com
Traumatic brain injury (TBI) is a well-known consequence of participation in activities such
as military combat or collision sports. But the wide variability in eliciting circumstances and …

The blood–brain barrier as a target in traumatic brain injury treatment

SC Thal, W Neuhaus - Archives of medical research, 2014 - Elsevier
Traumatic brain injury (TBI) is one of the most frequent causes of death in the young
population. Several clinical trials have unsuccessfully focused on direct neuroprotective …

An anatomically detailed and personalizable head injury model: Significance of brain and white matter tract morphological variability on strain

X Li, Z Zhou, S Kleiven - Biomechanics and modeling in mechanobiology, 2021 - Springer
Finite element head (FE) models are important numerical tools to study head injuries and
develop protection systems. The generation of anatomically accurate and subject-specific …

Repetitive mild traumatic brain injury in mice triggers a slowly develo** cascade of long-term and persistent behavioral deficits and pathological changes

X Xu, M Cowan, F Beraldo, A Schranz… - Acta neuropathologica …, 2021 - Springer
We have previously reported long-term changes in the brains of non-concussed varsity
rugby players using magnetic resonance spectroscopy (MRS), diffusion tensor imaging (DTI) …

Evaluation of tissue-level brain injury metrics using species-specific simulations

T Wu, M Hajiaghamemar, JS Giudice… - Journal of …, 2021 - liebertpub.com
Traumatic brain injury (TBI) is a significant public health burden, and the development of
advanced countermeasures to mitigate and prevent these injuries during automotive, sports …

Primary blast causes mild, moderate, severe and lethal TBI with increasing blast overpressures: Experimental rat injury model

V Mishra, M Skotak, H Schuetz, A Heller, J Haorah… - Scientific reports, 2016 - nature.com
Injury severity in blast induced Traumatic Brain Injury (bTBI) increases with blast
overpressure (BOP) and impulse in dose-dependent manner. Pure primary blast waves …

When physics meets biology: low and high-velocity penetration, blunt impact, and blast injuries to the brain

L Young, GT Rule, RT Bocchieri, TJ Walilko… - Frontiers in …, 2015 - frontiersin.org
The incidence of traumatic brain injuries (TBI) in the US has reached epidemic proportions
with well over 2 million new cases reported each year. TBI can occur in both civilians and …

Vascular and inflammatory factors in the pathophysiology of blast-induced brain injury

GA Elder, MA Gama Sosa, R De Gasperi… - Frontiers in …, 2015 - frontiersin.org
Blast-related traumatic brain injury (TBI) has received much recent attention because of its
frequency in the conflicts in Iraq and Afghanistan. This renewed interest has led to a rapid …

Integrating human and nonhuman primate data to estimate human tolerances for traumatic brain injury

T Wu, F Sato, J Antona-Makoshi… - Journal of …, 2022 - asmedigitalcollection.asme.org
Traumatic brain injury (TBI) contributes to a significant portion of the injuries resulting from
motor vehicle crashes, falls, and sports collisions. The development of advanced …

[HTML][HTML] Defining the biomechanical and biological threshold of murine mild traumatic brain injury using CHIMERA (Closed Head Impact Model of Engineered …

DR Namjoshi, WH Cheng, A Bashir, A Wilkinson… - Experimental …, 2017 - Elsevier
Abstract CHIMERA (Closed Head Impact Model of Engineered Rotational Acceleration) is a
recently described animal model of traumatic brain injury (TBI) that primarily produces …