Multipotent mesenchymal stromal cells (MSC) have been widely explored for cell-based
therapy of immune-mediated, inflammatory, and degenerative diseases, due to their …

Abstract Purpose of Review Cryopreservation and its associated freezing and thawing
procedures–short “freeze-thawing”–are among the final steps in economically viable …

Mitochondrial dysfunction and oxidative stress damage are hallmarks of osteoarthritis (OA).
Mesenchymal stem cell (MSC)-derived exosomes are important in intercellular mitochondria …

Mesenchymal stromal cells (MSCs) for basic research and clinical applications are
manufactured and developed as unique cell products by many different manufacturers and …

Considering the unique therapeutic potential of mesenchymal stem cells (MSCs), including
their immunosuppressive and immunomodulatory properties as well as their ability to …

Mesenchymal stromal cells (MSCs) possess profound immunomodulatory and regenerative
properties that are of clinical use in numerous clinical indications with unmet medical need …

Assays that can characterize MSC immune potency need to be identified for use in
advanced clinical trials. MSCs possess a number of putative regenerative and …

Background Immunomodulation by mesenchymal stromal cells (MSCs) can occur through
trophic factor mechanisms, however, intravenously infused MSCs are rapidly cleared from …

Mesenchymal stromal cells (MSCs) are administered locally to treat sites of inflammation.
Local delivery is known to cause MSCs to aggregate into “spheroids,” which alters gene …

Mesenchymal stromal cells (MSCs) are among of the most studied cell type for cellular
therapy thanks to the ease of isolation, cultivation, and the high ex vivo expansion potential …