Privileged structures have been widely used as an effective template for the research and
discovery of high value chemicals. Coumarin is a simple scaffold widespread in Nature and …

Inflammation is a natural process that is connected to various conditions and disorders such
as arthritis, psoriasis, cancer, infections, asthma, etc. Based on the fact that cyclooxygenase …

One of the best ways to design new biocidal agents is synthesizing hybrid molecules by
combining two or more bioactive moieties in a single molecular scaffold. So, new series of …

Based on the extensive biological activities of thiazole derivatives against different types of
diseases, we are interested in the effective part of many natural compounds, so we …

New efficient antimicrobial agents are urgently needed to combat invasive multidrug-
resistant pathogens infections. Structurally unique benzenesulfonyl thiazoloimines (BSTIs) …

Most chronic wounds suffer from infections, and their treatment is challenging. The usage of
antibiotics may lead to bacterial resistance and adverse side effects. Positively charged …

A novel series of substituted 4, 6-dimethyl-2-oxo-1-(thiazol-2-ylamino)-1, 2-dihydropyridine-
3-carbonitrile derivatives 6, 9, 13, 15, and 17 was synthesized in a good to excellent yield …

A novel series of the 2-pyridine substituted 3a-e and 4-pyridine substituted 4a-e thiazole
derivatives were synthesized, characterized, and evaluated for the biological activity …

Microbial infections are currently a widespread disease in hospitals and community health
centres and are a major cause of death worldwide. In pursuit of searching new antimicrobial …

A new series of triazole-thiazole hybrids were designed, synthesized by the Multi-
component reaction approach and evaluated in vitro antimicrobial activity. Most of the tested …