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Detecting balancing selection in genomes: limits and prospects
In spite of the long‐term interest in the process of balancing selection, its frequency in
genomes and evolutionary significance remain unclear due to challenges related to its …
genomes and evolutionary significance remain unclear due to challenges related to its …
Genetic architecture and balancing selection: the life and death of differentiated variants
Balancing selection describes any form of natural selection, which results in the persistence
of multiple variants of a trait at intermediate frequencies within populations. By offering up a …
of multiple variants of a trait at intermediate frequencies within populations. By offering up a …
Sex-dependent dominance at a single locus maintains variation in age at maturity in salmon
Males and females share many traits that have a common genetic basis; however, selection
on these traits often differs between the sexes, leading to sexual conflict,. Under such sexual …
on these traits often differs between the sexes, leading to sexual conflict,. Under such sexual …
The genomics of sexual conflict
Sexual dimorphism is a substantial contributor to the diversity observed in nature, extending
from elaborate traits to the expression level of individual genes. Sexual conflict and sexually …
from elaborate traits to the expression level of individual genes. Sexual conflict and sexually …
On the importance of balancing selection in plants
Balancing selection refers to a variety of selective regimes that maintain advantageous
genetic diversity within populations. We review the history of the ideas regarding the types of …
genetic diversity within populations. We review the history of the ideas regarding the types of …
Genome-wide sexually antagonistic variants reveal long-standing constraints on sexual dimorphism in fruit flies
The evolution of sexual dimorphism is constrained by a shared genome, leading to 'sexual
antagonism', in which different alleles at given loci are favoured by selection in males and …
antagonism', in which different alleles at given loci are favoured by selection in males and …
Negative frequency dependent selection unites ecology and evolution
From genes to communities, understanding how diversity is maintained remains a
fundamental question in biology. One challenging to identify, yet potentially ubiquitous …
fundamental question in biology. One challenging to identify, yet potentially ubiquitous …
Balancing selection in species with separate sexes: insights from Fisher's geometric model
How common is balancing selection, and what fraction of phenotypic variance is attributable
to balanced polymorphisms? Despite decades of research, answers to these questions …
to balanced polymorphisms? Despite decades of research, answers to these questions …
Male-biased gene expression resolves sexual conflict through the evolution of sex-specific genetic architecture
Many genes are subject to contradictory selection pressures in males and females, and
balancing selection resulting from sexual conflict has the potential to substantially increase …
balancing selection resulting from sexual conflict has the potential to substantially increase …
The search for sexually antagonistic genes: Practical insights from studies of local adaptation and statistical genomics
Sexually antagonistic (SA) genetic variation—in which alleles favored in one sex are
disfavored in the other—is predicted to be common and has been documented in several …
disfavored in the other—is predicted to be common and has been documented in several …