The global spread of drug resistance in bacteria requires new potent and safe antimicrobial
agents. Compounds containing the 1, 2, 4-triazole ring in their structure are characterised by …

The biological activity of Mannich bases, a structurally heterogeneous class of chemical
compounds that are generated from various substrates through the introduction of an …

Triazoles are heterocyclic compounds which have a five-membered ring of two carbon
atoms and three nitrogen atoms. These structures have been interest in the development of …

New 1-adamanyl-1, 3, 4-thiadiazole derivatives namely, 5-(1-adamantyl)-1, 3, 4-
thiadiazoline-2-thione 3, 5-(1-adamantyl)-3-(benzyl-or 4-substituted benzyl)-1, 3, 4 …

Background Triazole is an important heterocyclic moiety that occupies a unique position in
heterocyclic chemistry, due to its large number of biological activities. It exists in two isomeric …

The adamantane moiety has attracted significant attention since its discovery in 1933 due to
its remarkable structural, chemical, and medicinal properties. This molecule has a notable …

Abstract Different novel 1, 2, 4-triazolo [4, 3-b][1, 2, 4, 5] tetrazines and 1, 2, 4-triazolo [4, 3-
b][1, 2, 4] triazines have been obtained from heterocyclization of 3-substituted-4-amino-5 …

Abstract The reaction of 5-(1-adamantyl)-4-substituted-1, 2, 4-triazoline-3-thione 5a, b and
10a, b with formaldehyde solution and various primary aromatic amines or 1-substituted …

A series of novel myrtenal derivatives bearing 1, 2, 4-triazole moiety were designed and
synthesized by multi-step reactions in an attempt to develop potent antifungal agents. Their …

1, 2, 3-Triazoles are present in the structure of many natural compounds, and due to their
significant biological features, the synthesis of these compounds is of special importance in …