Marine natural products

JW Blunt, BR Copp, RA Keyzers, MHG Munro… - Natural Product …, 2015 - pubs.rsc.org
Covering: 2013. Previous review: Nat. Prod. Rep., 2014, 31, 160–258 This review covers the
literature published in 2013 for marine natural products (MNPs), with 982 citations (644 for …

[HTML][HTML] Antimicrobial compounds from microorganisms

C Amaning Danquah, PAB Minkah, I Osei Duah Junior… - Antibiotics, 2022 - mdpi.com
Antimicrobial resistance is an exigent public health concern owing to the emergence of
novel strains of human resistant pathogens and the concurrent rise in multi-drug resistance …

Molecular networking as a dereplication strategy

JY Yang, LM Sanchez, CM Rath, X Liu… - Journal of natural …, 2013 - ACS Publications
A major goal in natural product discovery programs is to rapidly dereplicate known entities
from complex biological extracts. We demonstrate here that molecular networking, an …

Harnessing the intracellular triacylglycerols for titer improvement of polyketides in Streptomyces

W Wang, S Li, Z Li, J Zhang, K Fan, G Tan, G Ai… - Nature …, 2020 - nature.com
Pharmaceutically important polyketides such as avermectin are mainly produced as
secondary metabolites during the stationary phase of growth of Streptomyces species in …

The intriguing chemistry and biology of sulfur-containing natural products from marine microorganisms (1987–2020)

Y Hai, MY Wei, CY Wang, YC Gu, CL Shao - Marine Life Science & …, 2021 - Springer
Natural products derived from marine microorganisms have received great attention as a
potential resource of new compound entities for drug discovery. The unique marine …

Recent advances in deep-sea natural products

D Skropeta, L Wei - Natural product reports, 2014 - pubs.rsc.org
Covering: 2009 to 2013. This review covers the 188 novel marine natural products
described since 2008, from deep-water (50–> 5000 m) marine fauna including bryozoa …

Culturable rare Actinomycetes: diversity, isolation and marine natural product discovery

R Subramani, W Aalbersberg - Applied microbiology and biotechnology, 2013 - Springer
Rare Actinomycetes from underexplored marine environments are targeted in drug
discovery studies due to the Actinomycetes' potentially huge resource of structurally diverse …

Deep sea actinomycetes and their secondary metabolites

M Kamjam, P Sivalingam, Z Deng, K Hong - Frontiers in Microbiology, 2017 - frontiersin.org
Deep sea is a unique and extreme environment. It is a hot spot for hunting marine
actinomycetes resources and secondary metabolites. The novel deep sea actinomycete …

Natural [4+ 2]-Cyclases

B Jeon, SA Wang, MW Ruszczycky, H Liu - Chemical reviews, 2017 - ACS Publications
[4+ 2]-Cycloadditions are increasingly being recognized in the biosynthetic pathways of
many structurally complex natural products. A relatively small collection of enzymes from …

Biosynthesis of ilamycins featuring unusual building blocks and engineered production of enhanced anti-tuberculosis agents

J Ma, H Huang, Y **e, Z Liu, J Zhao, C Zhang… - Nature …, 2017 - nature.com
Tuberculosis remains one of the world's deadliest communicable diseases, novel anti-
tuberculosis agents are urgently needed due to severe drug resistance and the co-epidemic …