Phenolic compounds: Current industrial applications, limitations and future challenges

BR Albuquerque, SA Heleno, MBPP Oliveira… - Food & function, 2021 - pubs.rsc.org
Phenolic compounds are natural bioactive molecules found mainly in plant tissues that have
shown interesting bioactivities, such as antioxidant, antimicrobial, anti-inflammatory, and …

Flavonoids as potential anti-inflammatory molecules: A review

JM Al-Khayri, GR Sahana, P Nagella, BV Joseph… - Molecules, 2022 - mdpi.com
Hydroxylated polyphenols, also called flavonoids, are richly present in vegetables, fruits,
cereals, nuts, herbs, seeds, stems, and flowers of numerous plants. They possess numerous …

Quercetin derivatives: Drug design, development, and biological activities, a review

SR Alizadeh, MA Ebrahimzadeh - European journal of medicinal chemistry, 2022 - Elsevier
More studies are needed to develop new drugs for problems associated with drug
resistance and unfavorable side effects. The natural flavonoid of quercetin revealed a wide …

Therapeutic potential of flavonoids in pain and inflammation: mechanisms of action, pre-clinical and clinical data, and pharmaceutical development

CR Ferraz, TT Carvalho, MF Manchope, NA Artero… - Molecules, 2020 - mdpi.com
Pathological pain can be initiated after inflammation and/or peripheral nerve injury. It is a
consequence of the pathological functioning of the nervous system rather than only a …

Recent advances in nanoformulations for quercetin delivery

EM Tomou, P Papakyriakopoulou, EM Saitani… - Pharmaceutics, 2023 - mdpi.com
Quercetin (QUE) is a flavonol that has recently received great attention from the research
community due to its important pharmacological properties. However, QUE's low solubility …

Inorganic nanoparticle-based advanced cancer therapies: Promising combination strategies

MJN Amaldoss, JL Yang, P Koshy, A Unnikrishnan… - Drug Discovery …, 2022 - Elsevier
Inorganic nanoparticles for drug delivery in cancer treatment offer many potential
advantages because they can maximize therapeutic effect through targeting ligands while …

Crosstalk between obesity, diabetes, and alzheimer's disease: Introducing quercetin as an effective triple herbal medicine

S Ebrahimpour, M Zakeri, A Esmaeili - Ageing research reviews, 2020 - Elsevier
Obesity and diabetes are the most common metabolic disorders, which are strongly related
to Alzheimer's disease (AD) in aging. Diabetes and obesity can lead to the accumulation of …

Quercetin attenuates neurotoxicity induced by iron oxide nanoparticles

A Bardestani, S Ebrahimpour, A Esmaeili… - Journal of …, 2021 - Springer
Iron oxide nanoparticles (IONPs) have been proposed as targeted carriers to deliver
therapeutic molecules in the central nervous system (CNS). However, IONPs may damage …

RETRACTED: Biosynthesis and characterization of iron oxide nanoparticles from Mentha spicata and screening its combating potential against Phytophthora infestans

S Khan, G Bibi, S Dilbar, A Iqbal, M Ahmad… - Frontiers in plant …, 2022 - frontiersin.org
Plant pathogens cause serious diseases to agricultural crops which lead to food insecurity in
the world. To combat plant pathogens, various strategies have been developed including …

Anti-oxidative, anti-inflammatory and anti-apoptotic effects of flavonols: targeting Nrf2, NF-κB and p53 pathways in neurodegeneration

M Jazvinšćak Jembrek, N Oršolić, L Mandić, A Sadžak… - Antioxidants, 2021 - mdpi.com
Neurodegenerative diseases are one of the leading causes of disability and death
worldwide. Intracellular transduction pathways that end in the activation of specific …