Mucin glycan foraging in the human gut microbiome
The availability of host and dietary carbohydrates in the gastrointestinal (GI) tract plays a key
role in sha** the structure-function of the microbiota. In particular, some gut bacteria have …
role in sha** the structure-function of the microbiota. In particular, some gut bacteria have …
The human gut microbiome: ecology and recent evolutionary changes
The human gastrointestinal tract is divided into sections, allowing digestion and nutrient
absorption in the proximal region to be separate from the vast microbial populations in the …
absorption in the proximal region to be separate from the vast microbial populations in the …
Utilization of major fucosylated and sialylated human milk oligosaccharides by isolated human gut microbes
ZT Yu, C Chen, DS Newburg - Glycobiology, 2013 - academic.oup.com
Human milk oligosaccharides (HMOS) are not digested in the proximal intestine. In distal
intestine, HMOS collectively modify the microbiota, but the response of individual bacteria to …
intestine, HMOS collectively modify the microbiota, but the response of individual bacteria to …
Genome-centric investigation of bile acid metabolizing microbiota of dairy cows and associated diet-induced functional implications
Although the importance of bile acid (BA)-related microbial strains and enzymes is
increasingly recognized for monogastric animals, a lack of knowledge about BA metabolism …
increasingly recognized for monogastric animals, a lack of knowledge about BA metabolism …
Molecular strategies for the utilisation of human milk oligosaccharides by infant gut-associated bacteria
LJ Kiely, K Busca, JA Lane… - FEMS Microbiology …, 2023 - academic.oup.com
A number of bacterial species are found in high abundance in the faeces of healthy breast-
fed infants, an occurrence that is understood to be, at least in part, due to the ability of these …
fed infants, an occurrence that is understood to be, at least in part, due to the ability of these …
Biochemical and structural basis of sialic acid utilization by gut microbes
A Bell, E Severi, CD Owen, D Latousakis… - Journal of Biological …, 2023 - ASBMB
The human gastrointestinal (GI) tract harbors diverse microbial communities collectively
known as the gut microbiota that exert a profound impact on human health and disease. The …
known as the gut microbiota that exert a profound impact on human health and disease. The …
Are pathogenic bacteria just looking for food? Metabolism and microbial pathogenesis
L Rohmer, D Hocquet, SI Miller - Trends in microbiology, 2011 - cell.com
It is interesting to speculate that the evolutionary drive for microbes to develop pathogenic
characteristics was to access the nutrient resources that animals provided. Animal …
characteristics was to access the nutrient resources that animals provided. Animal …
Utilisation of Mucin Glycans by the Human Gut Symbiont Ruminococcus gnavus Is Strain-Dependent
Commensal bacteria often have an especially rich source of glycan-degrading enzymes
which allow them to utilize undigested carbohydrates from the food or the host. The species …
which allow them to utilize undigested carbohydrates from the food or the host. The species …
Complex N-glycan breakdown by gut Bacteroides involves an extensive enzymatic apparatus encoded by multiple co-regulated genetic loci
J Briliūtė, PA Urbanowicz, AS Luis, A Baslé… - Nature …, 2019 - nature.com
Glycans are the major carbon sources available to the human colonic microbiota. Numerous
N-glycosylated proteins are found in the human gut, from both dietary and host sources …
N-glycosylated proteins are found in the human gut, from both dietary and host sources …
Elucidation of a sialic acid metabolism pathway in mucus-foraging Ruminococcus gnavus unravels mechanisms of bacterial adaptation to the gut
Sialic acid (N-acetylneuraminic acid (Neu5Ac)) is commonly found in the terminal location of
colonic mucin glycans where it is a much-coveted nutrient for gut bacteria, including …
colonic mucin glycans where it is a much-coveted nutrient for gut bacteria, including …