Coupling functions: universal insights into dynamical interaction mechanisms
The dynamical systems found in nature are rarely isolated. Instead they interact and
influence each other. The coupling functions that connect them contain detailed information …
influence each other. The coupling functions that connect them contain detailed information …
Mathematical modeling of circadian rhythms
Circadian rhythms are endogenous~ 24‐hr oscillations usually entrained to daily
environmental cycles of light/dark. Many biological processes and physiological functions …
environmental cycles of light/dark. Many biological processes and physiological functions …
GABA-mediated repulsive coupling between circadian clock neurons in the SCN encodes seasonal time
The mammalian suprachiasmatic nucleus (SCN) forms not only the master circadian clock
but also a seasonal clock. This neural network of∼ 10,000 circadian oscillators encodes …
but also a seasonal clock. This neural network of∼ 10,000 circadian oscillators encodes …
Distinct roles for GABA across multiple timescales in mammalian circadian timekee**
The suprachiasmatic nuclei (SCN), the central circadian pacemakers in mammals, comprise
a multiscale neuronal system that times daily events. We use recent advances in graphics …
a multiscale neuronal system that times daily events. We use recent advances in graphics …
Functional network inference of the suprachiasmatic nucleus
In the mammalian suprachiasmatic nucleus (SCN), noisy cellular oscillators communicate
within a neuronal network to generate precise system-wide circadian rhythms. Although the …
within a neuronal network to generate precise system-wide circadian rhythms. Although the …
Protein sequestration versus Hill‐type repression in circadian clock models
Circadian (∼ 24 h) clocks are self‐sustained endogenous oscillators with which organisms
keep track of daily and seasonal time. Circadian clocks frequently rely on interlocked …
keep track of daily and seasonal time. Circadian clocks frequently rely on interlocked …
Computational modeling of the cell-autonomous mammalian circadian oscillator
OA Podkolodnaya, NN Tverdokhleb… - BMC systems …, 2017 - Springer
This review summarizes various mathematical models of cell-autonomous mammalian
circadian clock. We present the basics necessary for understanding of the cell-autonomous …
circadian clock. We present the basics necessary for understanding of the cell-autonomous …
Synchronization of bioelectric oscillations in networks of nonexcitable cells: from single-cell to multicellular states
Biological networks use collective oscillations for information processing tasks. In particular,
oscillatory membrane potentials have been observed in nonexcitable cells and bacterial …
oscillatory membrane potentials have been observed in nonexcitable cells and bacterial …
Responses to spatial contrast in the mouse suprachiasmatic nuclei
A direct retinal projection targets the suprachiasmatic nucleus (SCN)(an important
hypothalamic control center). The accepted function of this projection is to convey …
hypothalamic control center). The accepted function of this projection is to convey …
A new phase model of the spatiotemporal relationships between three circadian oscillators in the brainstem
Abstract Analysis of ex vivo Per2 bioluminescent rhythm previously recorded in the mouse
dorsal vagal complex reveals a characteristic phase relationship between three distinct …
dorsal vagal complex reveals a characteristic phase relationship between three distinct …