Holotomography
Holotomography (HT) represents a 3D, label-free optical imaging methodology that
leverages refractive index as an inherent quantitative contrast for imaging. This technique …
leverages refractive index as an inherent quantitative contrast for imaging. This technique …
Quantitative phase imaging for medical diagnosis
Optical microscopy is an indispensable diagnostic tool in modern healthcare. As a prime
example, pathologists rely exclusively on light microscopy to investigate tissue morphology …
example, pathologists rely exclusively on light microscopy to investigate tissue morphology …
Spatial light interference microscopy: principle and applications to biomedicine
In this paper, we review spatial light interference microscopy (SLIM), a common-path, phase-
shifting interferometer, built onto a phase-contrast microscope, with white-light illumination …
shifting interferometer, built onto a phase-contrast microscope, with white-light illumination …
Quantitative phase imaging (QPI) in neuroscience
Quantitative phase imaging (QPI) is an emerging label-free modality that attracts significant
interest in biomedicine in general and neuroscience in particular. Based on the principle of …
interest in biomedicine in general and neuroscience in particular. Based on the principle of …
Label-free optical quantification of structural alterations in Alzheimer's disease
We present a wide-field quantitative label-free imaging of mouse brain tissue slices with sub-
micrometre resolution, employing holographic microscopy and an automated scanning …
micrometre resolution, employing holographic microscopy and an automated scanning …
Quantitative phase imaging for label-free analysis of cancer cells—focus on digital holographic microscopy
Z El-Schich, A Leida Mölder, A Gjörloff Wingren - Applied Sciences, 2018 - mdpi.com
To understand complex biological processes, scientists must gain insight into the function of
individual living cells. In contrast to the imaging of fixed cells, where a single snapshot of the …
individual living cells. In contrast to the imaging of fixed cells, where a single snapshot of the …
Complex refractive index of normal and malignant human colorectal tissue in the visible and near‐infrared
A multi‐wavelength prism coupling refractometer is utilized to measure the angular
reflectance of freshly excised human intestinal tissue specimens. Based on reflectance data …
reflectance of freshly excised human intestinal tissue specimens. Based on reflectance data …
Label-free quantitative evaluation of breast tissue using Spatial Light Interference Microscopy (SLIM)
Breast cancer is the most common type of cancer among women worldwide. The standard
histopathology of breast tissue, the primary means of disease diagnosis, involves manual …
histopathology of breast tissue, the primary means of disease diagnosis, involves manual …
Multimodal quantitative phase imaging with digital holographic microscopy accurately assesses intestinal inflammation and epithelial wound healing
P Lenz, M Brückner, S Ketelhut… - Journal of …, 2016 - pmc.ncbi.nlm.nih.gov
The incidence of inflammatory bowel disease, ie, Crohn's disease and Ulcerative colitis, has
significantly increased over the last decade. The etiology of IBD remains unknown and …
significantly increased over the last decade. The etiology of IBD remains unknown and …
Quantifying collagen fiber orientation in breast cancer using quantitative phase imaging
Tumor progression in breast cancer is significantly influenced by its interaction with the
surrounding stromal tissue. Specifically, the composition, orientation, and alignment of …
surrounding stromal tissue. Specifically, the composition, orientation, and alignment of …