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[HTML][HTML] Can MRI measure myelin? Systematic review, qualitative assessment, and meta-analysis of studies validating microstructural imaging with myelin histology
Recent years have seen an increased understanding of the importance of myelination in
healthy brain function and neuropsychiatric diseases. Non-invasive microstructural magnetic …
healthy brain function and neuropsychiatric diseases. Non-invasive microstructural magnetic …
Remyelination therapies: a new direction and challenge in multiple sclerosis
Multiple sclerosis is characterized by inflammatory activity that results in destruction of the
myelin sheaths that enwrap axons. The currently available medications for multiple sclerosis …
myelin sheaths that enwrap axons. The currently available medications for multiple sclerosis …
[HTML][HTML] Breastfeeding and early white matter development: A cross-sectional study
Does breastfeeding alter early brain development? The prevailing consensus from large
epidemiological studies posits that early exclusive breastfeeding is associated with …
epidemiological studies posits that early exclusive breastfeeding is associated with …
Promoting remyelination in multiple sclerosis
The greatest unmet need in multiple sclerosis (MS) are treatments that delay, prevent or
reverse progression. One of the most tractable strategies to achieve this is to therapeutically …
reverse progression. One of the most tractable strategies to achieve this is to therapeutically …
Map** infant brain myelination with magnetic resonance imaging
Myelination, the elaboration of myelin surrounding neuronal axons, is essential for normal
brain function. The development of the myelin sheath enables rapid synchronized …
brain function. The development of the myelin sheath enables rapid synchronized …
[HTML][HTML] Investigating white matter development in infancy and early childhood using myelin water faction and relaxation time map**
The elaboration of the myelinated white matter is essential for normal neurodevelopment,
establishing and mediating rapid communication pathways throughout the brain. These …
establishing and mediating rapid communication pathways throughout the brain. These …
Quantifying the local tissue volume and composition in individual brains with magnetic resonance imaging
Here, we describe a quantitative neuroimaging method to estimate the macromolecular
tissue volume (MTV), a fundamental measure of brain anatomy. By making measurements …
tissue volume (MTV), a fundamental measure of brain anatomy. By making measurements …
Contributions to magnetic susceptibility of brain tissue
This review discusses the major contributors to the subtle magnetic properties of brain tissue
and how they affect MRI contrast. With the increased availability of high‐field scanners, the …
and how they affect MRI contrast. With the increased availability of high‐field scanners, the …
Practical medical applications of quantitative MR relaxometry
Conventional MR images are qualitative, and their signal intensity is dependent on several
complementary contrast mechanisms that are manipulated by the MR hardware and …
complementary contrast mechanisms that are manipulated by the MR hardware and …
Diffusion tensor imaging for understanding brain development in early life
The human brain rapidly develops during the final weeks of gestation and in the first two
years following birth. Diffusion tensor imaging (DTI) is a unique in vivo imaging technique …
years following birth. Diffusion tensor imaging (DTI) is a unique in vivo imaging technique …