The lining of blood vessels is constantly exposed to mechanical forces exerted by blood flow
against the endothelium. Endothelial cells detect these tangential forces (ie, shear stress) …

Class B1 G protein-coupled receptors (GPCRs) are important regulators of many
physiological functions such as glucose homeostasis, which is mainly mediated by three …

Homomeric dimerization of metabotropic glutamate receptors (mGlus) is essential for the
modulation of their functions and represents a promising avenue for the development of …

The G protein-coupled receptors (GPCRs) play a pivotal role in numerous biological
processes as crucial cell membrane receptors. However, the dynamic mechanisms …

Human cytomegalovirus (HCMV) is a ubiquitous herpesvirus residing latently in a majority of
the population. While generally asymptomatic in healthy individuals, primary infection or …

The β2-adrenoceptor (β2AR) is a prototypical class A member of the G protein-coupled
receptor (GPCR) superfamily of membrane-bound receptors. Activation of the β2AR is …