Biological responses to physicochemical properties of biomaterial surface

M Rahmati, EA Silva, JE Reseland… - Chemical Society …, 2020 - pubs.rsc.org
Biomedical scientists use chemistry-driven processes found in nature as an inspiration to
design biomaterials as promising diagnostic tools, therapeutic solutions, or tissue …

The extracellular matrix in development

DAC Walma, KM Yamada - Development, 2020 - journals.biologists.com
As the crucial non-cellular component of tissues, the extracellular matrix (ECM) provides
both physical support and signaling regulation to cells. Some ECM molecules provide a …

Combating implant infections: shifting focus from bacteria to host

S Amin Yavari, SM Castenmiller… - Advanced …, 2020 - Wiley Online Library
The widespread use of biomaterials to support or replace body parts is increasingly
threatened by the risk of implant‐associated infections. In the quest for finding novel anti …

High-throughput methods in the discovery and study of biomaterials and materiobiology

L Yang, S Pijuan-Galito, HS Rho, AS Vasilevich… - Chemical …, 2021 - ACS Publications
The complex interaction of cells with biomaterials (ie, materiobiology) plays an increasingly
pivotal role in the development of novel implants, biomedical devices, and tissue …

Recent advances in scaffold design and material for vascularized tissue‐engineered bone regeneration

S Yin, W Zhang, Z Zhang, X Jiang - Advanced healthcare …, 2019 - Wiley Online Library
Bone tissue is a highly vascularized tissue and concomitant development of the vascular
system and mineralized matrix requires a synergistic interaction between osteogenesis and …

[HTML][HTML] Biomaterial-induced pathway modulation for bone regeneration

S Vermeulen, ZT Birgani, P Habibovic - Biomaterials, 2022 - Elsevier
Embryogenic developmental processes involve a tightly controlled regulation between
mechanical forces and biochemical cues such as growth factors, matrix proteins, and …

Calcium–zinc phosphate Chemical Conversion Coating facilitates the osteointegration of biodegradable zinc Alloy Implants by orchestrating macrophage phenotype

DW Zhao, CM Du, KQ Zuo, YX Zhao… - Advanced …, 2023 - Wiley Online Library
Zinc (Zn) alloys provide a new generation for orthopedic applications due to their essential
physiological effects and promising degradation properties. However, excessive release of …

Strontium-zinc phosphate chemical conversion coating improves the osseointegration of titanium implants by regulating macrophage polarization

DW Zhao, C Liu, KQ Zuo, P Su, LB Li, GY **ao… - Chemical Engineering …, 2021 - Elsevier
The immune response of peri-titanium (Ti) implants, which is mainly determined by the
surface properties of the Ti implant, may lead to a prolonged healing period and even …

The cytokine secretion profile of mesenchymal stromal cells is determined by surface structure of the microenvironment

DG Leuning, NRM Beijer, NA Du Fossé, S Vermeulen… - Scientific reports, 2018 - nature.com
Mesenchymal stromal cells (MSC) secrete factors that contribute to organ homeostasis and
repair in a tissue specific manner. For instance, kidney perivascular mesenchymal stromal …

High-throughput routes to biomaterials discovery

F Soheilmoghaddam, M Rumble… - Chemical …, 2021 - ACS Publications
Many existing clinical treatments are limited in their ability to completely restore decreased
or lost tissue and organ function, an unenviable situation only further exacerbated by a …