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Role of the CCL2-CCR2 axis in cardiovascular disease: Pathogenesis and clinical implications
H Zhang, K Yang, F Chen, Q Liu, J Ni, W Cao… - Frontiers in …, 2022 - frontiersin.org
The CCL2-CCR2 axis is one of the major chemokine signaling pathways that has received
special attention because of its function in the development and progression of …
special attention because of its function in the development and progression of …
Application of the nano-drug delivery system in treatment of cardiovascular diseases
Y Deng, X Zhang, H Shen, Q He, Z Wu… - … in bioengineering and …, 2020 - frontiersin.org
Cardiovascular diseases (CVDs) have become a serious threat to human life and health.
Though many drugs acting via different mechanism of action are available in the market as …
Though many drugs acting via different mechanism of action are available in the market as …
[HTML][HTML] Role of butyrate, a gut microbiota derived metabolite, in cardiovascular diseases: a comprehensive narrative review
Cardiovascular diseases (CVD) are major causes of death worldwide. Recently, new roles
for intestinal microbiota in pathology and treatment of CVD have been proposed. Butyrate, a …
for intestinal microbiota in pathology and treatment of CVD have been proposed. Butyrate, a …
Nanoparticles in the diagnosis and treatment of vascular aging and related diseases
Aging-induced alternations of vasculature structures, phenotypes, and functions are key in
the occurrence and development of vascular aging-related diseases. Multiple molecular and …
the occurrence and development of vascular aging-related diseases. Multiple molecular and …
miRNA nanotherapeutics for cancer
Highlights•MicroRNAs play a major role in cancer.•Several clinical trials with microRNA are
reported for cancer treatment.•Delivery of microRNA encounters several challenges.•We …
reported for cancer treatment.•Delivery of microRNA encounters several challenges.•We …
Non-coding RNAs in cardiovascular cell biology and atherosclerosis
Atherosclerosis underlies the predominant number of cardiovascular diseases and remains
a leading cause of morbidity and mortality worldwide. The development, progression and …
a leading cause of morbidity and mortality worldwide. The development, progression and …
Endothelial microRNAs regulating the NF‐κB pathway and cell adhesion molecules during inflammation
The surface of endothelial cells is covered with cell adhesion molecules, including E‐
selectin, intercellula adhesion molecule 1 (ICAM‐1), and vascular cell adhesion molecule 1 …
selectin, intercellula adhesion molecule 1 (ICAM‐1), and vascular cell adhesion molecule 1 …
More than an anticoagulant: Do heparins have direct anti-inflammatory effects?
The heparins, well-known for their anticoagulant properties, may also have anti-
inflammatory effects that could contribute to their effectiveness in the treatment of venous …
inflammatory effects that could contribute to their effectiveness in the treatment of venous …
Targeting immune cell recruitment in atherosclerosis
Atherosclerosis is the primary underlying cause of myocardial infarction and stroke.
Atherosclerotic cardiovascular disease is characterized by a chronic inflammatory reaction …
Atherosclerotic cardiovascular disease is characterized by a chronic inflammatory reaction …
Mouse models of atherosclerosis: a historical perspective and recent advances
Atherosclerosis represents a significant cause of morbidity and mortality in both the
developed and develo** countries. Animal models of atherosclerosis have served as …
developed and develo** countries. Animal models of atherosclerosis have served as …