Alzheimer's disease puzzle: delving into pathogenesis hypotheses

M Nasb, W Tao, N Chen - Aging and Disease, 2024 - pmc.ncbi.nlm.nih.gov
Alzheimer's disease (AD) is a prevalent neurodegenerative disease characterized by both
amnestic and non-amnestic clinical manifestations. It accounts for approximately 60-70% of …

The role of brain-derived neurotrophic factor (BDNF) in diagnosis and treatment of epilepsy, depression, schizophrenia, anorexia nervosa and Alzheimer's disease as …

A Gliwińska, J Czubilińska-Łada, G Więckiewicz… - Brain Sciences, 2023 - mdpi.com
Brain-derived neurotrophic factor (BDNF) belongs to the family of neurotrophins, which are
growth factors with trophic effects on neurons. BDNF is the most widely distributed …

The beneficial role of autophagy in multiple sclerosis: yes or no?

HM Al-Kuraishy, MS Jabir, AI Al-Gareeb, HM Saad… - Autophagy, 2024 - Taylor & Francis
Multiple sclerosis (MS) is a chronic progressive demyelinating disease of the central
nervous system (CNS) due to an increase of abnormal peripherally auto-reactive T …

MicroRNAs: pioneering regulators in Alzheimer's disease pathogenesis, diagnosis, and therapy

YB Li, Q Fu, M Guo, Y Du, Y Chen, Y Cheng - Translational Psychiatry, 2024 - nature.com
This article delves into Alzheimer's disease (AD), a prevalent neurodegenerative condition
primarily affecting the elderly. It is characterized by progressive memory and cognitive …

Advances in Alzheimer's disease: A multifaceted review of potential therapies and diagnostic techniques for early detection

M Sharma, P Pal, SK Gupta - Neurochemistry international, 2024 - Elsevier
Alzheimer's disease (AD) remains one of the most formidable neurological disorders,
affecting millions globally. This review provides a holistic overview of the therapeutic …

[HTML][HTML] MicroRNA alteration, application as biomarkers, and therapeutic approaches in neurodegenerative diseases

TPN Nguyen, M Kumar, E Fedele, G Bonanno… - International journal of …, 2022 - mdpi.com
MicroRNAs (miRNAs) are essential post-transcriptional gene regulators involved in various
neuronal and non-neuronal cell functions and play a key role in pathological conditions …

Microglial activation in metal neurotoxicity: impact in neurodegenerative diseases

MI Martínez-Hernández… - BioMed Research …, 2023 - Wiley Online Library
Neurodegenerative processes encompass a large variety of diseases with different
pathological patterns and clinical features, such as Alzheimer's and Parkinson's diseases …

MicroRNAs and synapse turnover in Alzheimer's disease

S Dalal, J Ramirez-Gomez, B Sharma, D Devara… - Ageing research …, 2024 - Elsevier
Alzheimer's Disease (AD) is a progressive neurodegenerative disorder characterized by the
accumulation of amyloid-beta plaques and neurofibrillary tangles in the brain, leading to …

microRNA-based biomarkers in Alzheimer's disease (AD)

Y Zhao, V Jaber, PN Alexandrov, A Vergallo… - Frontiers in …, 2020 - frontiersin.org
Alzheimer's disease (AD) is a multifactorial, age-related neurological disease characterized
by complex pathophysiological dynamics taking place at multiple biological levels, including …

[HTML][HTML] The brain–gut axis, an important player in alzheimer and parkinson disease: a narrative review

E Caradonna, R Nemni, A Bifone, P Gandolfo… - Journal of Clinical …, 2024 - mdpi.com
Neurodegenerative diseases, such as Alzheimer's disease (AD) and Parkinson's disease
(PD), are severe age-related disorders with complex and multifactorial causes. Recent …