Hemorrhagic transformation in ischemic stroke and the role of inflammation

E Spronk, G Sykes, S Falcione, D Munsterman… - Frontiers in …, 2021 - frontiersin.org
Hemorrhagic transformation (HT) is a common complication in patients with acute ischemic
stroke. It occurs when peripheral blood extravasates across a disrupted blood brain barrier …

Treatment and outcome of hemorrhagic transformation after intravenous alteplase in acute ischemic stroke: a scientific statement for healthcare professionals from the …

S Yaghi, JZ Willey, B Cucchiara, JN Goldstein… - Stroke, 2017 - Am Heart Assoc
Purpose—Symptomatic intracranial hemorrhage (sICH) is the most feared complication of
intravenous thrombolytic therapy in acute ischemic stroke. Treatment of sICH is based on …

Hemorrhagic transformation after ischemic stroke: mechanisms and management

JM Hong, DS Kim, M Kim - Frontiers in Neurology, 2021 - frontiersin.org
Symptomatic hemorrhagic transformation (HT) is one of the complications most likely to lead
to death in patients with acute ischemic stroke. HT after acute ischemic stroke is diagnosed …

Predictors for symptomatic intracranial hemorrhage after endovascular treatment of acute ischemic stroke

Y Hao, D Yang, H Wang, W Zi, M Zhang, Y Geng… - Stroke, 2017 - Am Heart Assoc
Background and Purpose—Symptomatic intracranial hemorrhage (SICH) pose a major
safety concern for endovascular treatment of acute ischemic stroke. This study aimed to …

Hemorrhagic transformation after ischemic stroke in animals and humans

GC Jickling, DZ Liu, B Stamova… - Journal of Cerebral …, 2014 - journals.sagepub.com
Hemorrhagic transformation (HT) is a common complication of ischemic stroke that is
exacerbated by thrombolytic therapy. Methods to better prevent, predict, and treat HT are …

Imaging of intracranial hemorrhage

JJ Heit, M Iv, M Wintermark - Journal of stroke, 2016 - pmc.ncbi.nlm.nih.gov
Intracranial hemorrhage is common and is caused by diverse pathology, including trauma,
hypertension, cerebral amyloid angiopathy, hemorrhagic conversion of ischemic infarction …

Collateral blood vessels in acute ischaemic stroke: a potential therapeutic target

A Shuaib, K Butcher, AA Mohammad… - The Lancet …, 2011 - thelancet.com
Ischaemic stroke results from acute arterial occlusion leading to focal hypoperfusion.
Thrombolysis is the only proven treatment. Advanced neuroimaging techniques allow a …

Collateral circulation in ischemic stroke: assessment tools and therapeutic strategies

OY Bang, M Goyal, DS Liebeskind - Stroke, 2015 - Am Heart Assoc
Conventional angiographic evaluation has advantages, including its reliable demonstration
of occlusion versus subtotal occlusion, well standardized recanalization grading, and high …

Combination of the immune modulator fingolimod with alteplase in acute ischemic stroke: a pilot trial

Z Zhu, Y Fu, D Tian, N Sun, W Han, G Chang, Y Dong… - Circulation, 2015 - Am Heart Assoc
Background—Inflammatory and immune responses triggered by brain ischemia worsen
clinical outcomes of stroke and contribute to hemorrhagic transformation, massive edema …

Collaterals at angiography and outcomes in the Interventional Management of Stroke (IMS) III trial

DS Liebeskind, TA Tomsick, LD Foster, SD Yeatts… - Stroke, 2014 - Am Heart Assoc
Background and Purpose—Endovascular strategies provide unique opportunity to correlate
angiographic measures of collateral circulation at the time of endovascular therapy. We …