Regulated cell death is a vital and dynamic process in multicellular organisms that maintains
tissue homeostasis and eliminates potentially dangerous cells. Apoptosis, one of the better …

Apoptosis is a sequential order of cell death occurring regularly to ensure a homeostatic
balance between the rate of cell formation and cell death. However, a misplaced of this …

Over the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated
guidelines for the definition and interpretation of cell death from morphological, biochemical …

The BCL-2 family of proteins controls cell death primarily by direct binding interactions that
regulate mitochondrial outer membrane permeabilization (MOMP) leading to the irreversible …

Breast cancer exhibits the highest global incidence among all tumor types. Regardless of
the type of breast cancer, metastasis is a crucial cause of poor prognosis. Anoikis, a form of …

The'hallmarks of cancer'are generally accepted as a set of genetic and epigenetic
alterations that a normal cell must accrue to transform into a fully malignant cancer. It follows …

Anoikis is a programmed cell death induced upon cell detachment from extracellular matrix,
behaving as a critical mechanism in preventing adherent-independent cell growth and …

BCL-2 family proteins are the regulators of apoptosis, but also have other functions. This
family of interacting partners includes inhibitors and inducers of cell death. Together they …

The Bcl-2 family of proteins controls a critical step in commitment to apoptosis by regulating
permeabilization of the mitochondrial outer membrane (MOM). The family is divided into …

Apoptosis, or programmed cell death, plays a pivotal role in the elimination of unwanted,
damaged, or infected cells in multicellular organisms and also in diverse biological …