Metalloenzymes catalyze a variety of reactions using a limited number of natural amino
acids and metallocofactors. Therefore, the environment beyond the primary coordination …

Specific interactions between proteins and DNA are fundamental to many biological
processes. In this review, we provide a revised view of protein-DNA interactions that …

Sequence logos are visually compelling ways of illustrating the biological properties of DNA,
RNA and protein sequences, yet it is currently difficult to generate and customize such logos …

Transcription activation by Escherichia coli catabolite activator protein (CAP) at each of two
classes of simple CAP-dependent promoters is understood in structural and mechanistic …

We present a set of protocols showing how to use the 3DNA suite of programs to analyze,
rebuild and visualize three-dimensional nucleic-acid structures. The software determines a …

Metabolically versatile free-living bacteria have global regulation systems that allow cells to
selectively assimilate a preferred compound among a mixture of several potential carbon …

A sequence element located immediately upstream of the TATA element, and having the
consensus sequence 5′-G/CG/CG/ACGCC-3′, affects the ability of transcription factor IIB …

Allosteric regulation is used as a very efficient mechanism to control protein activity in most
biological processes, including signal transduction, metabolism, catalysis and gene …

A detailed analysis of the DNA-binding sites of 26 proteins is presented using data from the
Nucleic Acid Database (NDB) and the Protein Data Bank (PDB). Chemical and physical …

Biocatalysis has become an important component of modern organic chemistry, presenting
an efficient and environmentally friendly approach to synthetic transformations. Advances in …