Transcriptional regulatory network of high-value active ingredients in medicinal plants

H Zheng, X Fu, J Shao, Y Tang, M Yu, L Li… - Trends in Plant …, 2023 - cell.com
High-value active ingredients in medicinal plants have attracted research attention because
of their benefits for human health, such as the antimalarial artemisinin, anticardiovascular …

Unlocking secrets of nature's chemists: Potential of CRISPR/Cas-based tools in plant metabolic engineering for customized nutraceutical and medicinal profiles

RM Shelake, AM Jadhav, PB Bhosale… - Plant Physiology and …, 2023 - Elsevier
Plant species have evolved diverse metabolic pathways to effectively respond to internal
and external signals throughout their life cycle, allowing adaptation to their sessile and …

Multiomics analyses of two Leonurus species illuminate leonurine biosynthesis and its evolution

P Li, MX Yan, P Liu, DJ Yang, ZK He, Y Gao, Y Jiang… - Molecular Plant, 2024 - cell.com
The Lamiaceae family is renowned for its terpenoid-based medicinal components, but
Leonurus, which has traditional medicinal uses, stands out for its alkaloid-rich composition …

Chromosome-level genome assembly of Salvia miltiorrhiza with orange roots uncovers the role of Sm2OGD3 in catalyzing 15,16-dehydrogenation of tanshinones

X Pan, Y Chang, C Li, X Qiu, X Cui, F Meng… - Horticulture …, 2023 - academic.oup.com
Salvia miltiorrhiza is well known for its clinical practice in treating heart and cardiovascular
diseases. Its roots, used for traditional Chinese medicine materials, are usually brick-red due …

Mitochondrial Genome Sequence of Salvia officinalis (Lamiales: Lamiaceae) Suggests Diverse Genome Structures in Cogeneric Species and Finds the Stop Gain of …

H Yang, H Chen, Y Ni, J Li, Y Cai, J Wang… - International Journal of …, 2023 - mdpi.com
Our previous study was the first to confirm that the predominant conformation of
mitochondrial genome (mitogenome) sequence of Salvia species contains two circular …

A chromosome-level genome assembly reveals that a bipartite gene cluster formed via an inverted duplication controls monoterpenoid biosynthesis in Schizonepeta …

C Liu, SJ Smit, J Dang, P Zhou, GT Godden, Z Jiang… - Molecular plant, 2023 - cell.com
Biosynthetic gene clusters (BGCs) are regions of a genome where genes involved in a
biosynthetic pathway are in proximity. The origin and evolution of plant BGCs as well as their …

Functional divergence of CYP76AKs shapes the chemodiversity of abietane-type diterpenoids in genus Salvia

J Hu, S Qiu, F Wang, Q Li, CL **ang, P Di, Z Wu… - Nature …, 2023 - nature.com
Abstract The genus Salvia L.(Lamiaceae) comprises myriad distinct medicinal herbs, with
terpenoids as one of their major active chemical groups. Abietane-type diterpenoids (ATDs) …

High‐quality chromosome‐level genome assembly and multi‐omics analysis of rosemary (Salvia rosmarinus) reveals new insights into the environmental and …

Y Lai, J Ma, X Zhang, X Xuan, F Zhu… - Plant Biotechnology …, 2024 - Wiley Online Library
High‐quality genome of rosemary (Salvia rosmarinus) represents a valuable resource and
tool for understanding genome evolution and environmental adaptation as well as its …

Multi‐omics analysis reveals the evolutionary origin of diterpenoid alkaloid biosynthesis pathways in Aconitum

D Zhao, Y Zhang, H Ren, Y Shi, D Dong… - Journal of integrative …, 2023 - Wiley Online Library
Diterpenoid alkaloids (DAs) have been often utilized in clinical practice due to their
analgesic and anti‐inflammatory properties. Natural DAs are prevalent in the family …

The chromosome‐scale assembly of the Salvia rosmarinus genome provides insight into carnosic acid biosynthesis

D Han, W Li, Z Hou, C Lin, Y **e, X Zhou… - The Plant …, 2023 - Wiley Online Library
Rosemary (Salvia rosmarinus) is considered a sacred plant because of its special fragrance
and is commonly used in cooking and traditional medicine. Here, we report a high‐quality …