E-cigarette toxicology

T Gordon, E Karey, ME Rebuli… - Annual review of …, 2022 - annualreviews.org
Since the spread of tobacco from the Americas hundreds of years ago, tobacco cigarettes
and, more recently, alternative tobacco products have become global products of nicotine …

Nicotine delivery and cigarette equivalents from va** a JUULpod

JJ Prochaska, EA Vogel, N Benowitz - Tobacco control, 2022 - tobaccocontrol.bmj.com
With patented nicotine salt technology, JUUL dominates the e-cigarette market. We
reviewed studies of JUUL's nicotine pharmacokinetic profile and studies quantifying nicotine …

Effect of exposure to e-cigarettes with salt vs free-base nicotine on the appeal and sensory experience of va**: a randomized clinical trial

AM Leventhal, DR Madden, N Peraza… - JAMA network …, 2021 - jamanetwork.com
Importance Alkaline free-base nicotine is bitter and a respiratory irritant. High-nicotine
electronic cigarette (e-cigarette) products contain acid additives that change nicotine from a …

Pulmonary effects of e-liquid flavors: a systematic review

F Effah, B Taiwo, D Baines, A Bailey… - Journal of Toxicology …, 2022 - Taylor & Francis
Electronic cigarettes (ECs) are purported to be tobacco harm-reduction products whose
degree of harm has been highly debated. EC use is considered less hazardous than …

[HTML][HTML] Thirdhand smoke from tobacco, e-cigarettes, cannabis, methamphetamine and cocaine: Partitioning, reactive fate, and human exposure in indoor …

K Yeh, L Li, F Wania, JPD Abbatt - Environment International, 2022 - Elsevier
A source of chemical exposure to humans, thirdhand smoke (THS) refers to the
contamination that persists indoors following the cessation of a smoking event. The …

E-Cigarette nicotine delivery among young adults by nicotine form, concentration, and flavor: a crossover randomized clinical trial

YJ Cho, T Mehta, A Hinton, R Sloan… - JAMA Network …, 2024 - jamanetwork.com
Importance Concerns have been raised about the abuse liability of modern e-cigarettes that
use acidic additives to form nicotine salts, making the inhalation of nicotine smoother than …

Cell-specific toxicity of short-term JUUL aerosol exposure to human bronchial epithelial cells and murine macrophages exposed at the air–liquid interface

R Pinkston, H Zaman, E Hossain, AL Penn, A Noël - Respiratory research, 2020 - Springer
Backgroud JUUL, an electronic nicotine delivery system (ENDS), which first appeared on the
US market in 2015, controled more than 75% of the US ENDS sales in 2018. JUUL-type …

Harmful and Potentially Harmful Constituents in E-Liquids and Aerosols from Electronic Nicotine Delivery Systems (ENDS)

SM Reilly, T Cheng, C Feng… - Chemical Research in …, 2024 - ACS Publications
In 2012, the US Food & Drug Administration (FDA) published an established list of 93
harmful and potentially harmful constituents (HPHCs) targeting four tobacco product types …

Addiction-related outcomes of nicotine and alcohol co-use: new insights following the rise in va**

JA Frie, CJ Nolan, JE Murray… - Nicotine and Tobacco …, 2022 - academic.oup.com
Purpose Nicotine and alcohol-containing products are some of the most commonly used
substances of abuse and are both leading causes of preventable death. These substances …

Comprehensive Dutch market data analysis shows that e-liquids with nicotine salts have both higher nicotine and flavour concentrations than those with free-base …

JLA Pennings, A Havermans… - Tobacco …, 2023 - tobaccocontrol.bmj.com
Objectives Recent years have seen an increase in e-liquids containing nicotine salts.
Nicotine salts are less harsh and bitter than free-base nicotine and therefore can facilitate …