Background Metagenomic next-generation sequencing (mNGS) has changed the diagnosis
landscape of lower respiratory tract infections (LRIs). With the development of newer …

Background Metagenomic next-generation sequencing (mNGS) for pathogen detection is
becoming increasingly available as a method to identify pathogens in cases of suspected …

The advent of next-generation sequencing (NGS) technologies has expanded our ability to
detect and analyze microbial genomes and has yielded novel molecular approaches for …

Infections lacking precise diagnosis are often caused by a rare or uncharacterized
pathogen, a combination of pathogens, or a known pathogen carrying undocumented or …

Metagenomic next-generation sequencing (mNGS) is an untargeted technique for
determination of microbial DNA/RNA sequences in a variety of sample types from patients …

Clinical metagenomics (CMg) is the process of sequencing nucleic acid of clinical samples
to obtain clinically relevant information such as the identification of microorganisms and their …

Metagenomic sequencing has emerged as a transformative tool in infectious disease
diagnosis, offering a comprehensive and unbiased approach to pathogen detection …

Introduction Metagenomic sequencing is increasingly being used in clinical settings for
difficult to diagnose cases. The performance of viral metagenomic protocols relies to a large …

Clinical metagenomics is the diagnostic approach with the broadest capacity to detect both
known and novel pathogens. Clinical metagenomics is costly to run and requires …

Background Clinical metagenomics involves the genomic sequencing of all microorganisms
in clinical samples ideally after depletion of human DNA to increase sensitivity and reduce …