Mice and rats emit ultrasonic vocalizations (USVs), which may express their arousal and
emotional states, to communicate with each other. There is continued scientific effort to …

Autism spectrum disorder (ASD) is a neurodevelopmental disorder. Several genetic causes
of ASD have been identified and this has enabled researchers to construct mouse models …

Preclinical studies of psychiatric disorders use animal models to investigate the impact of
environmental factors or genetic mutations on complex traits such as decision-making and …

Background A reduction of the number of parvalbumin (PV)-immunoreactive (PV+)
GABAergic interneurons or a decrease in PV immunoreactivity was reported in several …

Numerous genetic variants associated with MEF2C are linked to autism, intellectual
disability (ID) and schizophrenia (SCZ)–a heterogeneous collection of neurodevelopmental …

In 2005, Holy and Guo advanced the idea that male mice produce ultrasonic vocalizations
(USV) with some features similar to courtship songs of songbirds. Since then, studies …

Rodents emit ultrasonic vocalizations (USVs) to communicate the presence of positive or
negative emotional states and to coordinate social interactions. On this basis, USVs are …

Synaptopathies are a class of neurodevelopmental disorders caused by modification in
genes coding for synaptic proteins. These proteins oversee the process of …

Highlights•Mice do not show evidence of imitative vocal learning.•The lack of vocal learning
makes the mouse an excellent model system for understanding the genetic basis of human …

In rodent models of Autism Spectrum Disorders (ASD), the study of ultrasonic vocalizations
has provided the unique opportunity to evaluate social communication and interaction in …