Alzheimer's disease is the most common neurodegenerative disorder that can cause
dementia in elderly over 60 years of age. One of the disease hallmarks is oxidative stress …

Cancer is a multifaceted and complex pathology characterized by uncontrolled cell
proliferation and decreased apoptosis. Most cancers are recognized by an inflammatory …

During the implantation window, the endometrium becomes poised to transition to a
pregnant state, a process driven by differentiation of stromal cells into decidual cells (DC) …

Prion protein (PrP) protects neural cells against oxidative stress, hypoxia, ischemia, and
hypoglycemia. In the present study we confirm that cultured PrP‐deficient neurons are more …

Free radicals originate from both exogenous environmental sources and as by-products of
the respiratory chain and cellular oxygen metabolism. Sustained accumulation of free …

For decades now, sperm cryopreservation has been a pillar of assisted reproduction in
animals as well as humans. Nevertheless, the success of cryopreservation varies across …

Oxidative stress has been established as one of the main causes of male infertility and has
been implicated in many diseases associated with infertile men. It results from high …

Despite recent advances in the understanding of clinical aspects of sex differences in
Alzheimer's disease (AD), the underlying mechanisms, for instance, how sex modifies AD …

The spatiotemporal proteome of the intervertebral disc (IVD) underpins its integrity and
function. We present DIPPER, a deep and comprehensive IVD proteomic resource …

The multifaceted protein clusterin (CLU) has been challenging researchers for more than 35
years. The characterization of CLU as a molecular chaperone was one of the major …