Covering: up to 2022 Pentacyclic triterpenoids are important natural bioactive substances
that are widely present in plants and fungi. They have significant medicinal efficacy, play an …

Nuclear receptors (NRs) constitute a superfamily of ligand-activated transcription factors with
a paramount role in ubiquitous physiological functions such as metabolism, growth, and …

Background Cholestasis is a clinical syndrome with high incidence and few effective
treatments. Oleanolic acid (OA) is a triterpenoid compound with anti-cholestatic effects …

Neurodegenerative diseases are emerging as a global health concern in the current
scenario, and their association with mitochondrial defects has been a potential area of …

Achillea millefolium L., commonly known as yarrow, is a versatile and widely distributed
plant species with a rich history of ethnopharmacological significance. This study aimed to …

Ischemia/reperfusion (I/R) events are involved in the pathophysiology of numerous ocular
diseases. The purpose of this study was to test the hypothesis that betulinic acid protects …

Betulinic acid (BA) is a pentacyclic triterpene compound, which can be obtained by
separation, chemical synthesis and biotransformation. BA has excellent biological activities …

Pentacyclic triterpenes are important representatives of natural products that exhibit a wide
variety of biological activities. These activities suggest that these compounds may represent …

Mastic is a natural resin produced by Pistacia lentiscus L.(Anacardiaceae) with high
medicinal value and have been traditionally used as Uighur imported medicine for centuries …

Cardiovascular diseases (CVDs) involve dysfunction of the heart and blood vessels and
have become major health concerns worldwide. Multiple mechanisms may be involved in …