Comparative oncology: overcoming human cancer through companion animal studies

JH Oh, JY Cho - Experimental & Molecular Medicine, 2023 - nature.com
Comparative oncology is a field of study that has been recently adopted for studying cancer
and develo** cancer therapies. Companion animals such as dogs can be used to …

Comparative oncology: what dogs and other species can teach us about humans with cancer

JD Schiffman, M Breen - Philosophical Transactions of …, 2015 - royalsocietypublishing.org
Over 1.66 million humans (approx. 500/100 000 population rate) and over 4.2 million dogs
(approx. 5300/100 000 population rate) are diagnosed with cancer annually in the USA. The …

Canine lymphoma: a review

M Zandvliet - Veterinary Quarterly, 2016 - Taylor & Francis
Canine lymphoma (cL) is a common type of neoplasia in dogs with an estimated incidence
rate of 20–100 cases per 100,000 dogs and is in many respects comparable to non-Hodgkin …

Review of histological grading systems in veterinary medicine

G Avallone, R Rasotto, JK Chambers… - Veterinary …, 2021 - journals.sagepub.com
Tumor grading is a method to quantify the putative clinical aggressiveness of a neoplasm
based on specific histological features. A good grading system should be simple, easy to …

Tumors of the hemolymphatic system

VE Valli, D Bienzle, DJ Meuten - Tumors in domestic animals, 2016 - Wiley Online Library
The two general groups for tumors of the hemolymphatic system are lymphoid (lymphoma
and leukemia) and myeloid leukemias. The tumors in each can be characterized by their …

Dogs as a model for cancer

HL Gardner, JM Fenger… - Annual review of animal …, 2016 - annualreviews.org
Spontaneous cancers in client-owned dogs closely recapitulate their human counterparts
with respect to clinical presentation, histological features, molecular profiles, and response …

Tumors of the nervous system

RJ Higgins, AW Bollen, PJ Dickinson… - Tumors in domestic …, 2016 - Wiley Online Library
Primary neoplasms of the nervous system are relatively rare in most domestic animal
species with the exception of the dog and, to a lesser extent, the cat. Dogs and cats live …

Canine mammary tumors: classification, biomarkers, traditional and personalized therapies

N Nosalova, M Huniadi, Ľ Horňáková… - International Journal of …, 2024 - mdpi.com
In recent years, many studies have focused their attention on the dog as a proper animal
model for human cancer. In dogs, mammary tumors develop spontaneously, involving a …

Hematopoietic tumors

DM Vail, DH Thamm, JM Liptak - Withrow and MacEwen's …, 2019 - pmc.ncbi.nlm.nih.gov
Lymphoma (malignant lymphoma or lymphosarcoma) comprises a diverse group of
neoplasms that have in common their origin from lymphocytes. The neoplasms usually arise …

Canine lymphoma as a comparative model for human non-Hodgkin lymphoma: recent progress and applications

D Ito, AM Frantz, JF Modiano - Veterinary immunology and …, 2014 - Elsevier
The term “lymphoma” describes a heterogeneous group of disorders involving monoclonal
proliferation of malignant lymphocytes. As a group, lymphomas are among the most …