Left ventricular assist devices: challenges toward sustaining long-term patient care

M Schmid Daners, F Kaufmann, R Amacher… - Annals of biomedical …, 2017 - Springer
Over the last few decades, the left ventricular assist device (LVAD) technology has been
tremendously improved transitioning from large and noisy paracorporeal volume …

Medical therapy as compared to surgical device exchange for left ventricular assist device thrombosis: a systematic review and meta-analysis

JGY Luc, V Tchantchaleishvili, K Phan, SM Dunlay… - ASAIO …, 2019 - journals.lww.com
Pump thrombosis is a major adverse event in patients supported on continuous-flow left
ventricular assist devices (CF-LVAD). The aim of this systematic review and meta-analysis …

Continuous heart volume monitoring by fully implantable soft strain sensor

SA Dual, B Llerena Zambrano… - Advanced …, 2020 - Wiley Online Library
Cardiothoracic open‐heart surgery has revolutionized the treatment of cardiovascular
disease, the leading cause of death worldwide. After the surgery, hemodynamic and volume …

Standardized comparison of selected physiological controllers for rotary blood pumps: in vitro study

A Petrou, J Lee, S Dual, G Ochsner, M Meboldt… - Artificial …, 2018 - Wiley Online Library
Various physiological controllers for left ventricular assist devices (LVADs) have been
developed to prevent flow conditions that may lead to left ventricular (LV) suction and …

A novel multi-objective physiological control system for rotary left ventricular assist devices

A Petrou, M Monn, M Meboldt… - Annals of biomedical …, 2017 - Springer
Various control and monitoring algorithms have been proposed to improve the left-
ventricular assist device (LVAD) therapy by reducing the still-occurring adverse events. We …

A versatile hybrid mock circulation for hydraulic investigations of active and passive cardiovascular implants

A Petrou, M Granegger, M Meboldt, MS Daners - Asaio Journal, 2019 - journals.lww.com
During the development process of active or passive cardiovascular implants, such as
ventricular assist devices or vascular grafts, extensive in-vitro testing is required. The aim of …

A sensorless modular multiobjective control algorithm for left ventricular assist devices: A clinical pilot study

M Maw, T Schlöglhofer, C Marko, P Aigner… - Frontiers in …, 2022 - frontiersin.org
Background Contemporary Left Ventricular Assist Devices (LVADs) mainly operate at a
constant speed, only insufficiently adapting to changes in patient demand. Automatic …

[HTML][HTML] Genetic algorithm-based optimization framework for control parameters of ventricular assist devices

K Magkoutas, LN Rossato, M Heim… - … Signal Processing and …, 2023 - Elsevier
In this work, a novel, genetic algorithm-based optimization framework (GAOF) has been
developed and evaluated to optimize the control parameters of ventricular assist devices …

Cardiac output estimation: Online implementation for left ventricular assist device support

A Petrou, M Kanakis, K Magkoutas… - IEEE Transactions …, 2020 - ieeexplore.ieee.org
Objective: We present a novel pipeline that consists of various algorithms for the estimation
of the cardiac output (CO) during ventricular assist devices (VADs) support using a single …

A novel control method for rotary blood pumps as left ventricular assist device utilizing aortic valve state detection

D Petukhov, L Korn, M Walter… - BioMed Research …, 2019 - Wiley Online Library
A novel control method for rotary blood pumps is proposed relying on two different
objectives: regulation of pump flow in accordance with desired value and the maintenance …