Develo** recombinant antibodies by phage display against infectious diseases and toxins for diagnostics and therapy
KDR Roth, EV Wenzel, M Ruschig, S Steinke… - Frontiers in cellular …, 2021 - frontiersin.org
Antibodies are essential molecules for diagnosis and treatment of diseases caused by
pathogens and their toxins. Antibodies were integrated in our medical repertoire against …
pathogens and their toxins. Antibodies were integrated in our medical repertoire against …
The Peculiarities and Paradoxes of Plasmodium Heme Metabolism
PA Sigala, DE Goldberg - Annual review of microbiology, 2014 - annualreviews.org
For over a century, heme metabolism has been recognized to play a central role during
intraerythrocytic infection by Plasmodium parasites, the causative agent of malaria …
intraerythrocytic infection by Plasmodium parasites, the causative agent of malaria …
Multiple Plasmodium falciparum merozoite surface protein 1 complexes mediate merozoite binding to human erythrocytes
CS Lin, AD Uboldi, C Epp, H Bujard, T Tsuboi… - Journal of Biological …, 2016 - ASBMB
Successful invasion of human erythrocytes by Plasmodium falciparum merozoites is
required for infection of the host and parasite survival. The early stages of invasion are …
required for infection of the host and parasite survival. The early stages of invasion are …
Recombinant antibodies for diagnostics and therapy against pathogens and toxins generated by phage display
P Kuhn, V Fühner, T Unkauf… - Proteomics–Clinical …, 2016 - Wiley Online Library
Antibodies are valuable molecules for the diagnostic and treatment of diseases caused by
pathogens and toxins. Traditionally, these antibodies are generated by hybridoma …
pathogens and toxins. Traditionally, these antibodies are generated by hybridoma …
A Library of Plasmodium vivax Recombinant Merozoite Proteins Reveals New Vaccine Candidates and Protein-Protein Interactions
JB Hostetler, S Sharma, SJ Bartholdson… - PLoS neglected …, 2015 - journals.plos.org
Background A vaccine targeting Plasmodium vivax will be an essential component of any
comprehensive malaria elimination program, but major gaps in our understanding of P …
comprehensive malaria elimination program, but major gaps in our understanding of P …
Associations between prenatal malaria exposure, maternal antibodies at birth, and malaria susceptibility during the first year of life in Burkina Faso
HM Natama, G Moncunill, M Vidal… - Infection and …, 2023 - Am Soc Microbiol
In this study, we investigated how different categories of prenatal malaria exposure (PME)
influence levels of maternal antibodies in cord blood samples and the subsequent risk of …
influence levels of maternal antibodies in cord blood samples and the subsequent risk of …
The GMZ2 malaria vaccine: from concept to efficacy in humans
Introduction: GMZ2 is a recombinant protein consisting of conserved domains of GLURP and
MSP3, two asexual blood-stage antigens of Plasmodium falciparum, and is designed with …
MSP3, two asexual blood-stage antigens of Plasmodium falciparum, and is designed with …
B-Cell Epitope Map** of the Plasmodium falciparum Malaria Vaccine Candidate GMZ2.6c in a Naturally Exposed Population of the Brazilian Amazon
BO Baptista, ABL Souza, LS Oliveira, HAS Souza… - Vaccines, 2023 - mdpi.com
The GMZ2. 6c malaria vaccine candidate is a multi-stage P. falciparum chimeric protein that
contains a fragment of the sexual-stage Pf s48/45-6C protein genetically fused to GMZ2, an …
contains a fragment of the sexual-stage Pf s48/45-6C protein genetically fused to GMZ2, an …
Naturally acquired antibody response to a Plasmodium falciparum chimeric vaccine candidate GMZ2.6c and its components (MSP-3, GLURP, and Pfs48/45) in …
BO Baptista, ABL de Souza, EKP Riccio… - Malaria Journal, 2022 - Springer
Background The GMZ2. 6c malaria vaccine candidate is a multi-stage Plasmodium
falciparum chimeric protein which contains a fragment of the sexual-stage Pfs48/45-6C …
falciparum chimeric protein which contains a fragment of the sexual-stage Pfs48/45-6C …
[HTML][HTML] Plasmodium falciparum merozoite surface protein 3 as a vaccine candidate: a brief review
KCS Alves, JM Guimarães, MEM Almeida… - Revista do Instituto de …, 2022 - SciELO Brasil
Despite the many efforts of researchers around the world, there is currently no effective
vaccine for malaria. Numerous studies have been developed to find vaccine antigens that …
vaccine for malaria. Numerous studies have been developed to find vaccine antigens that …