Phase reduction and phase-based optimal control for biological systems: a tutorial
A powerful technique for the analysis of nonlinear oscillators is the rigorous reduction to
phase models, with a single variable describing the phase of the oscillation with respect to …
phase models, with a single variable describing the phase of the oscillation with respect to …
Recent advances in the analysis and control of large populations of neural oscillators
Many challenging problems that consider the analysis and control of neural brain rhythms
have been motivated by the advent of deep brain stimulation as a therapeutic treatment for a …
have been motivated by the advent of deep brain stimulation as a therapeutic treatment for a …
Pulsatile desynchronizing delayed feedback for closed-loop deep brain stimulation
High-frequency (HF) deep brain stimulation (DBS) is the gold standard for the treatment of
medically refractory movement disorders like Parkinson's disease, essential tremor, and …
medically refractory movement disorders like Parkinson's disease, essential tremor, and …
Greater accuracy and broadened applicability of phase reduction using isostable coordinates
The applicability of phase models is generally limited by the constraint that the dynamics of a
perturbed oscillator must stay near its underlying periodic orbit. Consequently, external …
perturbed oscillator must stay near its underlying periodic orbit. Consequently, external …
Neurodynamics
S Coombes, KCA Wedgwood - Texts in applied mathematics, 2023 - Springer
This is a book about 'Neurodynamics'. What we mean is that this is a book about how ideas
from dynamical systems theory have been developed and employed in recent years to give …
from dynamical systems theory have been developed and employed in recent years to give …
Augmented phase reduction of (not so) weakly perturbed coupled oscillators
While phase reduction is a tremendously useful tool for understanding the dynamics of
weakly perturbed limit cycle oscillators, its assumptions break down as perturbations …
weakly perturbed limit cycle oscillators, its assumptions break down as perturbations …
Optimal chaotic desynchronization for neural populations
A procedure is developed for finding an energy-optimal stimulus which gives a positive
Lyapunov exponent, and hence desynchronization, for a neural population. The procedure …
Lyapunov exponent, and hence desynchronization, for a neural population. The procedure …
Closed-loop deep brain stimulation by pulsatile delayed feedback with increased gap between pulse phases
OV Popovych, B Lysyansky, PA Tass - Scientific reports, 2017 - nature.com
Computationally it was shown that desynchronizing delayed feedback stimulation methods
are effective closed-loop techniques for the control of synchronization in ensembles of …
are effective closed-loop techniques for the control of synchronization in ensembles of …
Optimal phase control of biological oscillators using augmented phase reduction
We develop a novel optimal control algorithm to change the phase of an oscillator using a
minimum energy input, which also minimizes the oscillator's transversal distance to the …
minimum energy input, which also minimizes the oscillator's transversal distance to the …
Suppressing epileptic activity in a neural mass model using a closed-loop proportional-integral controller
Closed-loop control is a promising deep brain stimulation (DBS) strategy that could be used
to suppress high-amplitude epileptic activity. However, there are currently no analytical …
to suppress high-amplitude epileptic activity. However, there are currently no analytical …