Quetiapine fumarate (QTF) was approved for the treatment of schizophrenia and acute
manic episodes. QTF can also be used as an adjunctive treatment for major depressive …

The current research aims to improve the solubility of the poorly soluble drug, ie, ibuprofen,
by develo** self-emulsifying drug delivery systems (SEDDS) utilizing a twin screw melt …

This study aimed to investigate the amorphous stabilization of BCS Class II drugs using
mesoporous silica as a carrier to produce amorphous solid dispersions. Ibuprofen …

Background/Objectives: This study evaluates the efficacy of twin screw melt granulation
(TSMG), and hot-melt extrusion (HME) techniques in enhancing the solubility and …

Purpose Twin-screw wet granulation (TSWG) is a manufacturing process that offers several
advantages for the processing of water-insoluble active pharmaceutical ingredients (APIs) …

Objectives: This study aims to create an innovative self-microemulsifying drug delivery
system (SMEDDS) suppository for ibuprofen (IBU) using semisolid extrusion (SSE) three …

Vesicular system drug design has revitalised the efficacy of previous medications by
effectively regulating and sustaining their therapeutic action. The objective of this study is to …

Background: This study aimed to predict the pharmacokinetic and toxicological properties of
lead flavonoids from the roots of T. egregia [praecansone A (1) and pongachalcone (2)], and …

Sulfasalazine needs frequent daily dosing and the administration of numerous tablets per
day pose challenges to patient compliance, contributing to increased adverse effects and …

The contemporary investigation aimed to assess the hepatoprotective potential of Cissus
woodrowii (Stapf ex Cooke) Santapau against carbon tetrachloride-induced hepatotoxicity …