Intranasal nanotherapeutics for brain targeting and clinical studies in Parkinson's disease
Parkinson's disease (PD) is the second leading neurodegenerative disease globally,
impacting the quality of life of millions of people. It is estimated that the treatment cost of PD …
impacting the quality of life of millions of people. It is estimated that the treatment cost of PD …
Physiological and pathological factors affecting drug delivery to the brain by nanoparticles
The prevalence of neurological/neurodegenerative diseases, such as Alzheimer's disease is
known to be increasing due to an aging population and is anticipated to further grow in the …
known to be increasing due to an aging population and is anticipated to further grow in the …
Importance of nanoparticles for the delivery of antiparkinsonian drugs
Parkinson's disease (PD) affects around ten million people worldwide and is considered the
second most prevalent neurodegenerative disease after Alzheimer's disease. In addition …
second most prevalent neurodegenerative disease after Alzheimer's disease. In addition …
Intranasal delivery of mucoadhesive nanocarriers: a viable option for Parkinson's disease treatment?
Introduction: Intranasal drug delivery is a largely unexplored, promising approach for the
treatment of various neurological disorders. However, due to the challenging constraints …
treatment of various neurological disorders. However, due to the challenging constraints …
Development, characterization and pharmacokinetic evaluation of selegiline HCl loaded cubosomal thermoreversible mucoadhesive gel for nose to brain delivery
Abstract Selegiline HCl (SGH) is MAO-B inhibitor with limited bioavailability due to extensive
hepatic metabolism. Thus, this work aims to formulate and evaluate SGH loaded intranasal …
hepatic metabolism. Thus, this work aims to formulate and evaluate SGH loaded intranasal …
Central composite design–based optimization, fabrication, and pharmacodynamic assessment of sulfasalazine-loaded lipoidal nanoparticle-based hydrogel for the …
Rheumatoid arthritis is a progressive, chronic, immunological, and inflammatory disorder
that is distinguished by joint inflammation, joint tenderness, and synovial joint destruction …
that is distinguished by joint inflammation, joint tenderness, and synovial joint destruction …
Olopatadine hydrochloride loaded Kollidon® SR nanoparticles for ocular delivery: Nanosuspension formulation and in vitro–in vivo evaluation
Introduction Allergic eye diseases includes a spectrum of diseases, with each state being
characterized by a complicated immunopathology. In the present study, polymeric Kollidon® …
characterized by a complicated immunopathology. In the present study, polymeric Kollidon® …
[PDF][PDF] Emerging promise of nanoparticle-based treatment for Parkinson's disease
MM Rahman, KS Ferdous… - Biointerface Res. Appl …, 2020 - biointerfaceresearch.com
Neurodegenerative disorders are consequences of the deterioration of cells and tissues with
a mature undesirable way of life. The degenerative disease like Parkinson's disease (PD) …
a mature undesirable way of life. The degenerative disease like Parkinson's disease (PD) …
Potential applications of nanomedicine for treating Parkinson's disease
Parkinson's disease (PD) is an extrapyramidal, chronic progressive neurodegenerative
disorder. It affects approximately 5 million individuals globally, and by 2030, the prevalence …
disorder. It affects approximately 5 million individuals globally, and by 2030, the prevalence …
Nanobiotechnology in neurodegenerative diseases
J Jampílek, K Kráľová, P Novák, M Novák - Nanobiotechnology in …, 2019 - Springer
Abstract “Neurodegenerative disease” is a term for a variety of disorders that primarily affect
neurons in the human brain and spinal cord. These diseases are presently incurable and …
neurons in the human brain and spinal cord. These diseases are presently incurable and …