Effects of oxysterols on immune cells and related diseases
Oxysterols are the products of cholesterol oxidation. They have a wide range of effects on
several cells, organs, and systems in the body. Oxysterols also have an influence on the …
several cells, organs, and systems in the body. Oxysterols also have an influence on the …
[HTML][HTML] Innate lymphoid cell plasticity in mucosal infections
AA Korchagina, E Koroleva, AV Tumanov - Microorganisms, 2023 - mdpi.com
Mucosal tissue homeostasis is a dynamic process that involves multiple mechanisms
including regulation of innate lymphoid cells (ILCs). ILCs are mostly tissue-resident cells …
including regulation of innate lymphoid cells (ILCs). ILCs are mostly tissue-resident cells …
Circular RNA circTmem241 drives group III innate lymphoid cell differentiation via initiation of Elk3 transcription
N Liu, J He, D Fan, Y Gu, J Wang, H Li, X Zhu… - Nature …, 2022 - nature.com
Innate lymphoid cells (ILCs) exert important roles in host defense, tissue repair and
inflammatory diseases. However, how ILC lineage specification is regulated remains largely …
inflammatory diseases. However, how ILC lineage specification is regulated remains largely …
Vasoactive intestinal peptide promotes host defense against enteric pathogens by modulating the recruitment of group 3 innate lymphoid cells
HB Yu, H Yang, JM Allaire, C Ma… - Proceedings of the …, 2021 - National Acad Sciences
Group 3 innate lymphoid cells (ILC3s) control the formation of intestinal lymphoid tissues
and play key roles in intestinal defense. They express neuropeptide vasoactive intestinal …
and play key roles in intestinal defense. They express neuropeptide vasoactive intestinal …
Ornithine decarboxylase supports ILC3 responses in infectious and autoimmune colitis through positive regulation of IL-22 transcription
Group 3 innate lymphoid cells (ILC3s) are RORγT+ lymphocytes that are predominately
enriched in mucosal tissues and produce IL-22 and IL-17A. They are the innate counterparts …
enriched in mucosal tissues and produce IL-22 and IL-17A. They are the innate counterparts …
[HTML][HTML] Organoids capture tissue-specific innate lymphoid cell development in mice and humans
Organoid-based models of murine and human innate lymphoid cell precursor (ILCP)
maturation are presented. First, murine intestinal and pulmonary organoids are harnessed to …
maturation are presented. First, murine intestinal and pulmonary organoids are harnessed to …
Alarmins and innate lymphoid cells 2 activation: A common pathogenetic link connecting respiratory syncytial virus bronchiolitis and later wheezing/asthma?
GA Rossi, S Ballarini, P Salvati… - Pediatric Allergy and …, 2022 - Wiley Online Library
Severe respiratory syncytial virus (RSV) infection in infancy is associated with increased risk
of recurrent wheezing in childhood. Both acute and long‐term alterations in airway functions …
of recurrent wheezing in childhood. Both acute and long‐term alterations in airway functions …
Microbiota as key factors in inflammatory bowel disease
Inflammatory Bowel Disease (IBD) is characterized by prolonged inflammation of the
gastrointestinal tract, which is thought to occur due to dysregulation of the immune system …
gastrointestinal tract, which is thought to occur due to dysregulation of the immune system …
Washed microbiota transplantation promotes homing of group 3 innate lymphoid cells to the liver via the CXCL16/CXCR6 axis: a potential treatment for metabolic …
HJ Zhong, YP Zhuang, X **e, JY Song, SQ Wang… - Gut …, 2024 - Taylor & Francis
Despite the observed decrease in liver fat associated with metabolic-associated fatty liver
disease (MAFLD) in mice following fecal microbiota transplantation, the clinical effects and …
disease (MAFLD) in mice following fecal microbiota transplantation, the clinical effects and …
The impacts of cholesterol, oxysterols, and cholesterol lowering dietary compounds on the immune system
R Yanagisawa, C He, A Asai, M Hellwig… - International Journal of …, 2022 - mdpi.com
Cholesterol and its oxidized forms, oxysterols, are ingested from foods and are synthesized
de novo. Cholesterol and oxysterols influence molecular and cellular events and …
de novo. Cholesterol and oxysterols influence molecular and cellular events and …