As the population ages, spinal degeneration seriously affects quality of life in middle-aged
and elderly patients, and prevention and treatment remain challenging for clinical surgeons …

Tissue repair and regeneration is an interdisciplinary field focusing on develo** bioactive
substitutes aimed at restoring pristine functions of damaged, diseased tissues. Biomaterials …

In this paper, a pilot production process for mesenchymal stem/stromal freeze-dried
secretome was performed in a validated good manufacturing practice (GMP)-compliant cell …

Silver nanoparticles (AgNPs) are extensively applied for their broad-spectrum and excellent
antibacterial ability in recent years. Polydopamine (PDA) has great advantages for …

Regenerative medicine aims to restore the normal function of diseased or damaged cells,
tissues, and organs using a set of different approaches, including cell-based therapies. In …

With the aggravation of social aging and the increase in work intensity, the prevalence of
spinal degenerative diseases caused by intervertebral disc degeneration (IDD) has …

Standard treatments of chronic skin ulcers based on the direct application of dressings still
present several limits with regard to a complete tissue regeneration. Innovative strategies in …

Introduction: Initiation and progression of intervertebral disk degeneration are linked to
oxidative stress, with reactive oxygen species being a key factor. Therefore, as a potentially …

As a first step towards the production of functional cell sheets applicable for the regeneration
of gut muscle layer, microstructured bacterial cellulose (mBC) was assessed for its ability to …

Silk sericin (SS), a globular and water-soluble protein, showed to in vitro sustain the
proliferation of different mammalian cell lines, and to in vitro protect them from the oxidative …