Proteins exhibit structural fluctuations over decades of time scales. From the picosecond
side chain motions to aggregates that form over the course of minutes, characterizing protein …

Herpes simplex virus (HSV), a member of the Herpesviridae family, is a significant human
pathogen that results in mucocutaneous lesions in the oral cavity or genital infections …

Coronavirus disease 2019 (COVID-19) has spread across the world, and no specific
antiviral drugs have yet been approved to combat this disease. Favipiravir (FAV) is an …

In the active cytosine demethylation pathway, 5-methylcytosine (5mC) is oxidized
sequentially to 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5 …

DNA (2′-deoxyribonucleic acid) and RNA (ribonucleic acid) play diverse functional roles in
biology and disease. Despite being comprised primarily of only four cognate nucleobases …

DNA methyltransferases are drug targets for myelodysplastic syndrome (MDS), chronic
myelomonocytic leukemia (CMML), acute myelogenous leukemia (AML) and possibly β …

Within the framework of the classical Watson–Crick tautomeric hypothesis it has been
reliably established by quantum-chemical calculations that amino–imino tautomerization of …

Objective: A simple spectrophotometric method has been proposed for quantitative analysis
of favipiravir in bulk and pharmaceutical dosage form. Methods: New Fourier transform …

DNA-covered materials are important in technological applications such as biosensors and
microarrays, but obtaining structural information on surface-bound biomolecules is …

This study is intended to clarify in detail the tautomeric transformations of the wobble (w) G*
2AP (w) and A2AP (w) nucleobase mispairs involving 2-aminopurine (2AP) into the Watson …