Synaptic memory and CaMKII

RA Nicoll, H Schulman - Physiological reviews, 2023 - journals.physiology.org
Ca2+/calmodulin-dependent protein kinase II (CaMKII) and long-term potentiation (LTP)
were discovered within a decade of each other and have been inextricably intertwined ever …

A brief history of long-term potentiation

RA Nicoll - neuron, 2017 - cell.com
Since the discovery of long-term potentiation (LTP) in 1973, thousands of papers have been
published on this intriguing phenomenon, which provides a compelling cellular model for …

LTP induction by structural rather than enzymatic functions of CaMKII

JE Tullis, ME Larsen, NL Rumian, RK Freund… - Nature, 2023 - nature.com
Learning and memory are thought to require hippocampal long-term potentiation (LTP), and
one of the few central dogmas of molecular neuroscience that has stood undisputed for …

CaM kinase: still inspiring at 40

KU Bayer, H Schulman - Neuron, 2019 - cell.com
Summary The Ca 2+/calmodulin (CaM)-dependent protein kinase II (CaMKII) was touted as
a memory molecule, even before its involvement in long-term potentiation (LTP) was shown …

Engineering a memory with LTD and LTP

S Nabavi, R Fox, CD Proulx, JY Lin, RY Tsien… - Nature, 2014 - nature.com
It has been proposed that memories are encoded by modification of synaptic strengths
through cellular mechanisms such as long-term potentiation (LTP) and long-term depression …

Monosomes actively translate synaptic mRNAs in neuronal processes

A Biever, C Glock, G Tushev, E Ciirdaeva, T Dalmay… - Science, 2020 - science.org
INTRODUCTION RNA sequencing and in situ hybridization have revealed the presence of
an unexpectedly high number of RNA species in neuronal dendrites and axons, and many …

Neural plasticity and behavior–sixty years of conceptual advances

JD Sweatt - Journal of neurochemistry, 2016 - Wiley Online Library
This brief review summarizes 60 years of conceptual advances that have demonstrated a
role for active changes in neuronal connectivity as a controller of behavior and behavioral …

Long-term potentiation: from CaMKII to AMPA receptor trafficking

BE Herring, RA Nicoll - Annual review of physiology, 2016 - annualreviews.org
For more than 20 years, we have known that Ca2+/calmodulin-dependent protein kinase
(CaMKII) activation is both necessary and sufficient for the induction of long-term …

The molecular biology of memory: cAMP, PKA, CRE, CREB-1, CREB-2, and CPEB

ER Kandel - Molecular brain, 2012 - Springer
The analysis of the contributions to synaptic plasticity and memory of cAMP, PKA, CRE,
CREB-1, CREB-2, and CPEB has recruited the efforts of many laboratories all over the …

Long‐term plasticity in the hippocampus: maintaining within and 'tagging'between synapses

MZ Bin Ibrahim, A Benoy, S Sajikumar - The FEBS journal, 2022 - Wiley Online Library
Synapses between neurons are malleable biochemical structures, strengthening and
diminishing over time dependent on the type of information they receive. This phenomenon …