The role of the blood–brain barrier during neurological disease and infection

A Patabendige, D Janigro - Biochemical Society Transactions, 2023 - portlandpress.com
A healthy brain is protected by the blood–brain barrier (BBB), which is formed by the
endothelial cells that line brain capillaries. The BBB plays an extremely important role in …

COVID-19 is associated with changes in brain function and structure: A multimodal meta-analysis of neuroimaging studies

Z Guo, S Sun, S **ao, G Chen, P Chen, Z Yang… - Neuroscience & …, 2024 - Elsevier
The actual role of coronavirus disease 2019 (COVID-19) in brain damage has been
increasingly reported, necessitating a meta-analysis to collate and summarize the …

Injury-specific factors in the cerebrospinal fluid regulate astrocyte plasticity in the human brain

S Sirko, C Schichor, P Della Vecchia, F Metzger… - Nature Medicine, 2023 - nature.com
The glial environment influences neurological disease progression, yet much of our
knowledge still relies on preclinical animal studies, especially regarding astrocyte …

SARS-CoV-2 brainstem encephalitis in human inherited DBR1 deficiency

YH Chan, V Lundberg, J Le Pen, J Yuan… - Journal of Experimental …, 2024 - rupress.org
Inherited deficiency of the RNA lariat–debranching enzyme 1 (DBR1) is a rare etiology of
brainstem viral encephalitis. The cellular basis of disease and the range of viral …

Pitfalls and biases in neuroepidemiological studies of COVID-19 and the nervous system: a critical appraisal of the current evidence and future directions

E Beghi, A Ivashynka, G Logroscino, FF de Oliveira… - Journal of …, 2023 - Springer
Background Neurological manifestations frequently occur in individuals with COVID-19,
manifesting during the acute phase, persisting beyond the resolution of acute symptoms …

[HTML][HTML] Sex differences in the outcome of critically Ill patients with COVID-19-An international multicenter critical care consortium study

L Premraj, NA Weaver, SA Ahmad, N White, G Whitman… - Heart & Lung, 2024 - Elsevier
Background Sex differences in severe acute respiratory syndrome coronavirus-2 (SARS-
CoV-2) susceptibility, illness severity, and hospital course are widely acknowledged. The …

Guillain–Barré syndrome: immunopathogenesis and therapeutic targets

S Liu, WW Zhang, L Jia, HL Zhang - Expert Opinion on Therapeutic …, 2024 - Taylor & Francis
ABSTRACT Introduction Guillain–Barré syndrome (GBS) is a group of acute immune-
mediated disorders in the peripheral nervous system. Both infectious and noninfectious …

Stroke in critically ill patients with respiratory failure due to COVID-19: Disparities between low-middle and high-income countries

D Battaglini, TL Kelly, M Griffee, J Fanning, L Premraj… - Heart & lung, 2024 - Elsevier
Purpose We aimed to compare the incidence of stroke in low-and middle-income countries
(LMICs) versus high-income countries (HICs) in critically ill patients with COVID-19 and its …

Neurological complications of critically ill COVID-19 patients

R Sonneville, NS Dangayach… - Current Opinion in …, 2023 - journals.lww.com
Neurological complications of critically ill COVID-19 patien... : Current Opinion in Critical Care
Neurological complications of critically ill COVID-19 patients : Current Opinion in Critical Care …

Neuroproteomic Analysis after SARS-CoV-2 Infection Reveals Overrepresented Neurodegeneration Pathways and Disrupted Metabolic Pathways

I Basak, R Harfoot, JE Palmer, A Kumar… - Biomolecules, 2023 - mdpi.com
Besides respiratory illness, SARS-CoV-2, the causative agent of COVID-19, leads to
neurological symptoms. The molecular mechanisms leading to neuropathology after SARS …