Midkine (MK) and pleiotrophin (PTN) are low molecular weight proteins with closely related
structures. They are mainly composed of two domains held by disulfide bridges, and there …

The midkine (MK) family consists of only two members, namely heparin-binding growth
factors MK and pleiotrophin (PTN). During embryogenesis, MK is highly expressed in the …

Midkine is a heparin-binding cytokine or a growth factor with a molecular weight of 13 kDa.
Midkine binds to oversulfated structures in heparan sulfate and chondroitin sulfate. The …

ABSTRACT The 37/67‐kDa laminin receptor (LAMR/RPSA) was originally identified as a 67‐
kDa binding protein for laminin, an extracellular matrix glycoprotein that provides cellular …

The 67LR (67 kDa laminin receptor) is a cell-surface receptor with high affinity for its primary
ligand. Its role as a laminin receptor makes it an important molecule both in cell adhesion to …

Midkine (MK) is a heparin‐binding growth factor or cytokine and forms a small protein family,
the other member of which is pleiotrophin. MK enhances survival, migration, cytokine …

Ligand-receptor internalization has been traditionally regarded as part of the cellular
desensitization system. Low-density lipoprotein receptor-related protein (LRP) is a large …

The growth factor midkine (MK) is a cytokine that inhibits the attachment of human
immunodeficiency virus particles by a mechanism similar to the nucleolin binding HB-19 …

Midkine (MK) and pleiotrophin (PTN) belong to the subfamily of heparin binding growth
factors. They have ca. 50% structural homology, with similar C-and N-domains as well as …

Midkine (MK) is a heparin-binding cytokine, and promotes growth, survival, migration and
other activities of target cells. After describing the general properties of MK, this review …