The history of brain drug delivery is reviewed beginning with the first demonstration, in 1914,
that a drug for syphilis, salvarsan, did not enter the brain, due to the presence of a blood …

Cognitive impairment in schizophrenia involves a broad array of nonsocial and social
cognitive domains. It is a core feature of the illness, and one with substantial implications for …

Despite widespread reports that intranasal application of oxytocin has a variety of behavioral
effects, very little of the huge amounts applied intranasally appears to reach the …

Recognition of other's emotions influences the way social animals interact and adapt to the
environment. The neuropeptide oxytocin (OXT) has been implicated in different aspects of …

The “Reading the Mind in the Eyes” test (Eyes test) is an advanced test of theory of mind.
Typical sex difference has been reported (ie, female advantage). Individuals with autism …

Background There is increasing interest in oxytocin as a therapeutic to treat social deficits in
autism spectrum disorders (ASD). The aim of this study was to investigate the efficacy of a …

Social cognition has become recognized as an important driver of functional outcomes and
overall recovery in patients with schizophrenia, mediating the relationship between …

Adequate drug delivery across the blood–brain barrier (BBB) is a critical factor in treating
central nervous system (CNS) disorders. Inspired by swimming fish and the microstructure of …

Schizophrenia is a form of mental disorder that is behaviorally characterized by abnormal
behavior, such as social function deficits or other behaviors that are disconnected from …

Efforts to develop psychosocial interventions that specifically target social cognition in
schizophrenia spectrum disorders began nearly two decades ago. The field has matured …