Neuroinflammation and oxidative stress in the pathogenesis of autism spectrum disorder

N Usui, H Kobayashi, S Shimada - International journal of molecular …, 2023 - mdpi.com
Autism spectrum disorder (ASD) is a neurodevelopmental disorder (NDD) characterized by
impairments in social communication, repetitive behaviors, restricted interests, and …

Effects of air pollution on the nervous system and its possible role in neurodevelopmental and neurodegenerative disorders

LG Costa, TB Cole, K Dao, YC Chang, J Coburn… - Pharmacology & …, 2020 - Elsevier
Recent extensive evidence indicates that air pollution, in addition to causing respiratory and
cardiovascular diseases, may also negatively affect the brain and contribute to central …

Oxidative stress in autism spectrum disorder—current progress of mechanisms and biomarkers

X Liu, J Lin, H Zhang, NU Khan, J Zhang… - Frontiers in …, 2022 - frontiersin.org
Autism spectrum disorder (ASD) is a type of neurodevelopmental disorder that has been
diagnosed in an increasing number of children around the world. Existing data suggest that …

Altered gut microbial profile is associated with abnormal metabolism activity of Autism Spectrum Disorder

Z Dan, X Mao, Q Liu, M Guo, Y Zhuang, Z Liu… - Gut …, 2020 - Taylor & Francis
ABSTRACT Autism Spectrum Disorder (ASD) is a severe neurodevelopmental disorder. To
enhance the understanding of the gut microbiota structure in ASD children at different ages …

The multifaceted therapeutic role of N-acetylcysteine (NAC) in disorders characterized by oxidative stress

G Raghu, M Berk, PA Campochiaro… - Current …, 2021 - benthamdirect.com
Oxidative stress, which results in the damage of diverse biological molecules, is a ubiquitous
cellular process implicated in the etiology of many illnesses. The sulfhydryl-containing …

Environmental risk factors for autism: an evidence-based review of systematic reviews and meta-analyses

A Modabbernia, E Velthorst, A Reichenberg - Molecular autism, 2017 - Springer
Background According to recent evidence, up to 40–50% of variance in autism spectrum
disorder (ASD) liability might be determined by environmental factors. In the present paper …

Biomarkers in stress related diseases/disorders: diagnostic, prognostic, and therapeutic values

K Dhama, SK Latheef, M Dadar, HA Samad… - Frontiers in molecular …, 2019 - frontiersin.org
Various internal and external factors negatively affect the homeostatic equilibrium of
organisms at the molecular to the whole-body level, inducing the so-called state of stress …

Clinical relevance of biomarkers of oxidative stress

J Frijhoff, PG Winyard, N Zarkovic… - Antioxidants & redox …, 2015 - liebertpub.com
Significance: Oxidative stress is considered to be an important component of various
diseases. A vast number of methods have been developed and used in virtually all diseases …

Oxidative stress in autism spectrum disorder

G Bjørklund, NA Meguid, MA El-Bana, AA Tinkov… - Molecular …, 2020 - Springer
Abstract According to the United States Centers for Disease Control and Prevention (CDC),
as of July 11, 2016, the reported average incidence of children diagnosed with an autism …

[HTML][HTML] Neurological, psychiatric, and biochemical aspects of thiamine deficiency in children and adults

S Dhir, M Tarasenko, E Napoli, C Giulivi - Frontiers in psychiatry, 2019 - frontiersin.org
Thiamine (vitamin B1) is an essential nutrient that serves as a cofactor for a number of
enzymes, mostly with mitochondrial localization. Some thiamine-dependent enzymes are …