Pseudomonas aeruginosa: Infections, Animal Modeling, and Therapeutics

SJ Wood, TM Kuzel, SH Shafikhani - Cells, 2023 - mdpi.com
Pseudomonas aeruginosa is an important Gram-negative opportunistic pathogen which
causes many severe acute and chronic infections with high morbidity, and mortality rates as …

Multidrug resistance (MDR): A widespread phenomenon in pharmacological therapies

A Catalano, D Iacopetta, J Ceramella, D Scumaci… - Molecules, 2022 - mdpi.com
Multidrug resistance is a leading concern in public health. It describes a complex phenotype
whose predominant feature is resistance to a wide range of structurally unrelated cytotoxic …

Pseudomonas aeruginosa: An Audacious Pathogen with an Adaptable Arsenal of Virulence Factors

I Jurado-Martín, M Sainz-Mejías… - International journal of …, 2021 - mdpi.com
Pseudomonas aeruginosa is a dominant pathogen in people with cystic fibrosis (CF)
contributing to morbidity and mortality. Its tremendous ability to adapt greatly facilitates its …

[HTML][HTML] Stimuli-responsive peptide assemblies: design, self-assembly, modulation, and biomedical applications

R Mu, D Zhu, S Abdulmalik, S Wijekoon, G Wei… - Bioactive materials, 2024 - Elsevier
Peptide molecules have design flexibility, self-assembly ability, high biocompatibility, good
biodegradability, and easy functionalization, which promote their applications as versatile …

The mechanism of ferroptosis and its related diseases

S Feng, D Tang, Y Wang, X Li, H Bao, C Tang… - Molecular …, 2023 - Springer
Ferroptosis, a regulated form of cellular death characterized by the iron-mediated
accumulation of lipid peroxides, provides a novel avenue for delving into the intersection of …

Antibiotic resistance in Pseudomonas aeruginosa–Mechanisms, epidemiology and evolution

J Botelho, F Grosso, L Peixe - Drug resistance updates, 2019 - Elsevier
Antibiotics are powerful drugs used in the treatment of bacterial infections. The inappropriate
use of these medicines has driven the dissemination of antibiotic resistance (AR) in most …

Pseudomonas aeruginosa epidemic high-risk clones and their association with horizontally-acquired β-lactamases: 2020 update

E del Barrio-Tofiño, C López-Causapé… - International journal of …, 2020 - Elsevier
Pseudomonas aeruginosa global clones associated with multidrug-resistant (MDR) and
extensively drug-resistant (XDR) phenotypes, denominated high-risk clones, are a growing …

Size and charge adaptive clustered nanoparticles targeting the biofilm microenvironment for chronic lung infection management

Y Gao, J Wang, M Chai, X Li, Y Deng, Q **, J Ji - ACS nano, 2020 - ACS Publications
Chronic lung infection caused by bacterial biofilms is an extremely serious clinical problem,
which can lead to the failure of antibiotic therapy. Although nanoparticles have shown great …

Genomic and Metabolic Characteristics of the Pathogenicity in Pseudomonas aeruginosa

T De Sousa, M Hébraud, MLNE Dapkevicius… - International journal of …, 2021 - mdpi.com
In recent years, the effectiveness of antimicrobials in the treatment of Pseudomonas
aeruginosa infections has gradually decreased. This pathogen can be observed in several …

Pseudomonas aeruginosa biofilms and their partners in crime

MM Cendra Gascón… - Biotechnology …, 2021 - upcommons.upc.edu
Pseudomonas aeruginosa biofilms and the capacity of the bacterium to coexist and interact
with a broad range of microorganisms have a substantial clinical impact. This review focuses …