Fluid transport in the brain
The brain harbors a unique ability to, figuratively speaking, shift its gears. During
wakefulness, the brain is geared fully toward processing information and behaving, while …
wakefulness, the brain is geared fully toward processing information and behaving, while …
Development and functions of the choroid plexus–cerebrospinal fluid system
The choroid plexus (ChP) is the principal source of cerebrospinal fluid (CSF), which has
accepted roles as a fluid cushion and a sink for nervous system waste in vertebrates …
accepted roles as a fluid cushion and a sink for nervous system waste in vertebrates …
[HTML][HTML] Human pluripotent stem cell-derived neural cells and brain organoids reveal SARS-CoV-2 neurotropism predominates in choroid plexus epithelium
Neurological complications are common in patients with COVID-19. Although severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), the causal pathogen of COVID-19, has …
respiratory syndrome coronavirus 2 (SARS-CoV-2), the causal pathogen of COVID-19, has …
Human CNS barrier-forming organoids with cerebrospinal fluid production
INTRODUCTION The choroid plexus is a secretory epithelial tissue of the central nervous
system (CNS) responsible for cerebrospinal fluid (CSF) production and functions as a barrier …
system (CNS) responsible for cerebrospinal fluid (CSF) production and functions as a barrier …
[HTML][HTML] Generation of functional hippocampal neurons from self-organizing human embryonic stem cell-derived dorsomedial telencephalic tissue
H Sakaguchi, T Kadoshima, M Soen, N Narii… - Nature …, 2015 - nature.com
The develo** dorsomedial telencephalon includes the medial pallium, which goes on to
form the hippocampus. Generating a reliable source of human hippocampal tissue is an …
form the hippocampus. Generating a reliable source of human hippocampal tissue is an …
[HTML][HTML] Self-organized cerebral organoids with human-specific features predict effective drugs to combat Zika virus infection
The human cerebral cortex possesses distinct structural and functional features that are not
found in the lower species traditionally used to model brain development and disease …
found in the lower species traditionally used to model brain development and disease …
Emergence and developmental roles of the cerebrospinal fluid system
RM Fame, MK Lehtinen - Developmental cell, 2020 - cell.com
We summarize recent work illuminating how cerebrospinal fluid (CSF) regulates brain
function. More than a protective fluid cushion and sink for waste, the CSF is an integral CNS …
function. More than a protective fluid cushion and sink for waste, the CSF is an integral CNS …
Generating human neural diversity with a multiplexed morphogen screen in organoids
Morphogens choreograph the generation of remarkable cellular diversity in the develo**
nervous system. Differentiation of stem cells in vitro often relies upon the combinatorial …
nervous system. Differentiation of stem cells in vitro often relies upon the combinatorial …
Map** the ethical issues of brain organoid research and application
In 2008, researchers created human three-dimensional neural tissue–known as the
pioneering work of “brain organoids.” In recent years, some researchers have transplanted …
pioneering work of “brain organoids.” In recent years, some researchers have transplanted …
Choroid plexus pathophysiology
This review examines the crucial roles of the choroid plexus (ChP) in central nervous system
(CNS) pathology, emphasizing its involvement in disease mechanisms and therapeutic …
(CNS) pathology, emphasizing its involvement in disease mechanisms and therapeutic …