[HTML][HTML] Uric acid in the pathogenesis of metabolic, renal, and cardiovascular diseases: a review

UAAS El Din, MM Salem, DO Abdulazim - Journal of advanced research, 2017‏ - Elsevier
The association between uric acid (UA) on one side and systemic hypertension (Htn),
dyslipidemia, glucose intolerance, overweight, fatty liver, renal disease and cardiovascular …

Serum uric acid levels and multiple health outcomes: umbrella review of evidence from observational studies, randomised controlled trials, and Mendelian …

X Li, X Meng, M Timofeeva, I Tzoulaki, KK Tsilidis… - Bmj, 2017‏ - bmj.com
Objective To map the diverse health outcomes associated with serum uric acid (SUA) levels.
Design Umbrella review. Data sources Medline, Embase, Cochrane Database of Systematic …

Elevated uric acid increases the risk for kidney disease

RP Obermayr, C Temml, G Gutjahr… - Journal of the …, 2008‏ - journals.lww.com
Recent epidemiologic studies suggest that uric acid predicts the development of new-onset
kidney disease, but it is unclear whether uric acid is an independent risk factor. In this study …

Serum concentrations of uric acid and the metabolic syndrome among US children and adolescents

ES Ford, C Li, S Cook, HK Choi - Circulation, 2007‏ - ahajournals.org
Background—The association between concentrations of uric acid and the metabolic
syndrome in children and adolescents remains incompletely understood. The objective of …

Fabrication of an efficient and sensitive colorimetric biosensor based on Uricase/Th-MOF for uric acid sensing in biological samples

A Badoei-Dalfard, N Sohrabi, Z Karami… - Biosensors and …, 2019‏ - Elsevier
Recently, nanomaterial-based artificial enzymes have expected abundant consideration
because of cheap, accessibility, and respectable stability. In this study, we report a Th-MOF …

Relationship of uric acid with progression of kidney disease

M Chonchol, MG Shlipak, R Katz, MJ Sarnak… - American Journal of …, 2007‏ - Elsevier
BACKGROUND: Uric acid levels are increased in patients with kidney dysfunction. We
tested the hypothesis that uric acid may be associated with kidney disease progression …

A review of enzymatic uric acid biosensors based on amperometric detection

PE Erden, E Kılıç - Talanta, 2013‏ - Elsevier
This review summarizes the studies carried on the development of amperometric uric acid
biosensors over the past twenty years. Sensing principles, enzyme immobilization …

Hyperuricemia has increased the risk of progression of chronic kidney disease: propensity score matching analysis from the KNOW-CKD study

TR Oh, HS Choi, CS Kim, EH Bae, SK Ma, SA Sung… - Scientific reports, 2019‏ - nature.com
The prevalence of hyperuricemia and chronic kidney disease (CKD) has been steadily
increasing. The role of hyperuricemia and efficacy of uric acid-lowering agents against CKD …

Uric acid is a risk factor for ischemic stroke and all-cause mortality in the general population: a gender specific analysis from The Tromsø Study

HM Storhaug, JV Norvik, I Toft, BO Eriksen… - BMC cardiovascular …, 2013‏ - Springer
Background The role of serum uric acid as an independent predictor of cardiovascular
disease and death is uncertain in the general population. Adjustments for additional …

Uric acid, the metabolic syndrome, and renal disease

P Cirillo, W Sato, S Reungjui, M Heinig… - Journal of the …, 2006‏ - journals.lww.com
Metabolic syndrome, characterized by truncal obesity, hypertriglyceridemia, elevated BP,
and insulin resistance, is recognized increasingly as a major risk factor for kidney disease …