Peptide and protein nanoparticle conjugates: versatile platforms for biomedical applications

CD Spicer, C Jumeaux, B Gupta… - Chemical Society …, 2018 - pubs.rsc.org
Peptide–and protein–nanoparticle conjugates have emerged as powerful tools for
biomedical applications, enabling the treatment, diagnosis, and prevention of disease. In …

Lipoprotein-inspired nanoparticles for cancer theranostics

KK Ng, JF Lovell, G Zheng - Accounts of chemical research, 2011 - ACS Publications
Over hundreds of millions of years, animals have evolved endogenous lipoprotein
nanoparticles for shuttling hydrophobic molecules to different parts of the body. In the last 70 …

EGF receptor-targeted nanocarriers for enhanced cancer treatment

AM Master, A Sen Gupta - Nanomedicine, 2012 - Taylor & Francis
The 'nanomedicine'approach has revolutionized cancer therapy by enabling the packaging
of therapeutic agents within engineered nanovehicles that can specifically accumulate …

In vivo studies of nanostructure‐based photosensitizers for photodynamic cancer therapy

SH Voon, LV Kiew, HB Lee, SH Lim, MI Noordin… - Small, 2014 - Wiley Online Library
Animal models, particularly rodents, are major translational models for evaluating novel
anticancer therapeutics. In this review, different types of nanostructure‐based …

Cetuximab conjugated O-carboxymethyl chitosan nanoparticles for targeting EGFR overexpressing cancer cells

S Maya, LG Kumar, B Sarmento, NS Re**old… - Carbohydrate …, 2013 - Elsevier
Nanoparticle mediated delivery of antineoplastic agents, functionalized with monoclonal
antibodies has achieved extraordinary potential in cancer therapy. The objective of this …

Targeted imaging of EGFR overexpressed cancer cells by brightly fluorescent nanoparticles conjugated with cetuximab

M Gao, H Su, G Lin, S Li, X Yu, A Qin, Z Zhao, Z Zhang… - Nanoscale, 2016 - pubs.rsc.org
To improve the treatment efficiency and reduce side effects in cancer therapy, accurate
diagnosis of cancer cell types at a molecular level is highly desirable. Fluorescent …

Receptor mediated targeting of EGF-conjugated alginate-PAMAM nanoparticles to lung adenocarcinoma: 2D/3D in vitro and in vivo evaluation

E Ilhan-Ayisigi, P Saglam-Metiner, E Sanci… - International Journal of …, 2024 - Elsevier
Abstract Carboplatin (cis-diamine (1, 1-cyclobutandicarboxylaso)‑platinum (II)) is a second-
generation antineoplastic drug, which is widely used for chemotherapy of lung, colon …

Critical parameters for particle-based pulmonary delivery of chemotherapeutics

A Dabbagh, NH Abu Kasim, CH Yeong… - Journal of aerosol …, 2018 - liebertpub.com
Targeted delivery of chemotherapeutics through the respiratory system is a potential
approach to improve drug accumulation in the lung tumor, while decreasing their negative …

A brightly red emissive AIEgen and its antibody conjugated nanoparticles for cancer cell targeting imaging

H Su, Z Deng, Y Liu, Y Zhao, H Liu, Z Zhao… - Materials Chemistry …, 2022 - pubs.rsc.org
Antibody decorated nanoparticles with brightly red emissions are promising probes for
targeted detection of cancer cells due to their excellent specificity, deep penetration depth …

Reaction of perrhenate with phthalocyanine derivatives in the presence of reducing agents and rhenium oxide nanoparticles in biomedical applications

S Ntsimango, S Gandidzanwa, SV Joseph… - …, 2022 - Wiley Online Library
A novel alternative route to access rhenium (V)− phthalocyanine complexes through direct
metalation of metal‐free phthalocyanines (H2Pcs) with a rhenium (VII) salt in the presence of …